Aminoguanidine bicarbonate

Aminoguanidine bicarbonate
  • CAS No.:2582-30-1
Other grades of this product :
Aminoguanidine bicarbonate Basic information
Product Name:Aminoguanidine bicarbonate
Synonyms:Aminoguanidine bicarbonate ;Aminoguanidine hydrogen carbonate;AMINOGUANIDINE BICARBONATE CRYSTALLINE;1-AMINOGUANIDINIUM HYDROGEN CARBONATE OE;Aminoguanidine bicarbonate, 98.50%;1-AMINOGUANIDINE BICARBONATE;1-AMINOGUANIDINE HYDROGEN CARBONATE;1-AMINOGUANIDINIUM HYDROGEN CARBONATE;GUANYLHYDRAZINE BICARBONATE
CAS:2582-30-1
MF:C2H8N4O3
MW:136.11
EINECS:219-956-7
Product Categories:white powder;Pharmaceutical Intermediates;2582-30-1
Mol File:2582-30-1.mol
Aminoguanidine bicarbonate Chemical Properties
Melting point 170-172 °C (dec.)(lit.)
density 1,6 g/cm3
storage temp. Store below +30°C.
solubility H2O: soluble2.7g/L at 20°C
form Crystalline Powder
pka6.19[at 20 ℃]
color White to off-white
PH8.9 (5g/l, H2O, 20℃)
Water Solubility <5 g/L (20 ºC)
BRN 3569869
InChIKeyOTXHZHQQWQTQMW-UHFFFAOYSA-N
LogP-6.61 at 25℃
CAS DataBase Reference2582-30-1(CAS DataBase Reference)
EPA Substance Registry SystemCarbonic acid, compd. with hydrazinecarboximidamide (1:1) (2582-30-1)
Safety Information
Hazard Codes Xi,Xn,N
Risk Statements 52/53-43-36/37/38-20/21/22-51/53
Safety Statements 22-24/25-37-24-36-26-36/37
RIDADR UN3077
WGK Germany 2
RTECS FG1772000
Autoignition Temperature245 °C
TSCA Yes
HazardClass 9
PackingGroup III
HS Code 29280090
ToxicityLD50 orally in Rabbit: > 5000 mg/kg
MSDS Information
ProviderLanguage
Aminoguanidine bicarbonate English
SigmaAldrich English
ACROS English
ALFA English
Aminoguanidine bicarbonate Usage And Synthesis
Chemical PropertiesWhite to off-white crystalline powder. It is almost insoluble in water, alcohol and other acids.
UsesAminoguanidine bicarbonate (AGB) is of practical importance because of its use in dyes, dispersants, explosives and other commercial applications. It is used in the synthesis of antitumor agents and antileukemic activity. Also used in the synthesis of neuraminidase inhibitors in the inhibition of influenze.
ApplicationAminoguanidine bicarbonate is an inhibitor of NOS (nitric oxide synthase). Aminoguanidine bicarbonate is used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5.
Biochem/physiol ActionsAminoguanidine bicarbonate protects the cells infected with adenovirus from chromosomal damage. Aminoguanidine is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum.
SynthesisA synthesis method of aminoguanidine bicarbonate includes reacting an acidic aqueous hydrazine hydrate solution with calcium cyanamide in an elevated temperature to produce an aminoguanidine solution, recovering the solution, and reacting therewith an alkali metal bicarbonate to produce relatively high purity aminoguanidine bicarbonate.

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