4-(2-Chloroethyl)morpholine hydrochloride

4-(2-Chloroethyl)morpholine hydrochloride
  • CAS No.:3647-69-6

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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4-(2-Chloroethyl)morpholine hydrochloride Basic information
Product Name:4-(2-Chloroethyl)morpholine hydrochloride
Synonyms:4-(2-chloroethyl)-morpholinhydrochloride;MOCPRF;MORPHOLINOETHYL CHLORIDE HYDROCHLORIDE;N-(2-CHLOROETHYL)MORPHOLINE HYDROCHLORIDE;N-(2-CHLORETHYL)-MORPHOLINIUM CHLORIDE;4-(2-CHLOROETHYL)MORPHOLINE HYDROCHLORIDE;2-MORPHOLINOETHYL CHLORIDE HYDROCHLORIDE;2-CHLOROETHYLMORPHOLINE HYDROCHLORIDE
CAS:3647-69-6
MF:C6H13Cl2NO
MW:186.08
EINECS:222-881-2
Product Categories:Aromatic Morpholines;Building Blocks;C4 to C10;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Morpholines/Thiomorpholines;Heterocycles;Pyridines
Mol File:3647-69-6.mol
4-(2-Chloroethyl)morpholine hydrochloride Chemical Properties
Melting point 180-185 °C (dec.)(lit.)
storage temp. Store below +30°C.
form Hygroscopic Crystalline Powder
color White to beige
PH4.5-5 (10g/l, H2O, 20℃)
Water Solubility soluble
Sensitive Hygroscopic
BRN 3684083
InChIKeyNBJHDLKSWUDGJG-UHFFFAOYSA-N
CAS DataBase Reference3647-69-6(CAS DataBase Reference)
EPA Substance Registry SystemMorpholine, 4-(2-chloroethyl)-, hydrochloride (3647-69-6)
Safety Information
Hazard Codes T
Risk Statements 21-25-34-43-52/53
Safety Statements 26-36/37/39-45-61
RIDADR UN 2923 8/PG 3
WGK Germany 2
RTECS QE0260000
Autoignition Temperature365 °C
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29349990
ToxicityLD50 orally in Rabbit: 96 mg/kg LD50 dermal Rat 1502 mg/kg
MSDS Information
ProviderLanguage
2-Morpholinoethyl chloride hydrochloride English
SigmaAldrich English
ACROS English
ALFA English
4-(2-Chloroethyl)morpholine hydrochloride Usage And Synthesis
Chemical PropertiesWhite to beige crystalline powder
Uses4-(2-Chloroethyl)morpholine hydrochloride (MOC) is used as intermediate for the synthesis of pharmaceuticals (e.g. floredil, morinamide, nimorazole and pholcodine). Product Data Sheet
Uses4-(2-Chloroethyl)morpholine is used in the preparation of potential DNA cross-linking antitumor agents as well as synthetic opiate analogues. 4-(2-Chloroethyl)morpholine may possess sickle-cell hemogl obin aggregation inhibiting-activity.
Uses4-(2-Chloroethyl)morpholine hydrochloride (MOC) is used as intermediate for the synthesis of pharmaceuticals (e.g. floredil, morinamide, nimorazole and pholcodine). It is also used as Agrochemical Intermediates, dyestuff Intermediates.
Safety ProfileExperimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cland NOx.
4-(2-Chloroethyl)morpholine hydrochloride Preparation Products And Raw materials
Raw materials2-Morpholinoethanol
Preparation Products4-(2-MORPHOLIN-4-YL-ETHOXY)-BENZOIC ACID-->4-(2-Chloroethyl)morpholine

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