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| Acriflavine hydrochloride Basic information |
| Product Name: | Acriflavine hydrochloride | | Synonyms: | LISTERIA SELECTIVE SUPPLEMENT UVM-II;LISTERIA PALCAM SELECTIVE SUPPLEMENT;EUFLAVINE;EUFLAVIN HYDROCHLORIDE;CI 46000;Acriflavine DiHCl (Mixture of AcriflaviniuM Chloride with Proflavine);Acriflavine hydrochloride, 98.5%;Acrifiavine Hcl | | CAS: | 8063-24-9 | | MF: | C27H28Cl4N6 | | MW: | 578.36 | | EINECS: | 1312995-182-4 | | Product Categories: | | Mol File: | 8063-24-9.mol |
| Acriflavine hydrochloride Chemical Properties |
| Melting point | 260 °C | | storage temp. | +2°C TO | | solubility | H2O: soluble1mg/mL | | form | Powder | | color | Red-brown | | PH Range | 2 | | Water Solubility | Soluble in water, dimethyl sulfoxide and methanol. | | Merck | 123 | | BRN | 6265525 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChIKey | VWXAJKFSYJFBIW-UHFFFAOYSA-N |
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ACROS
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| Acriflavine hydrochloride Usage And Synthesis |
| Chemical Properties | reddish-brown crystalline powder | | Uses | Acriflavine is an topical antiseptic agent and has also been used for the treatment of external fungal infections. | | Uses | Acriflavine Hydrochloride acts as an intercalating dye and also reported to inhibit mitochondriogenesis. It is an antiseptic and has been used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously. | | Purification Methods | Purify it by dissolving in 50 parts of H2O, shaking with a small excess of freshly precipitated and washed Ag2O. The mixture is set aside overnight at 0o and filtered. The cake is not washed. The pH of the filtrate is adjusted to 7.0 with HCl and evaporated to dryness. The residue is then crystallised twice from MeOH, twice from H2O and dried at 120o. at 452nm has a log value of 4.67. Itis ared max powder which readily absorbs H2O. The solubility is increased in the presence of proflavin. The dihydrochloride is a deep red crystalline powder. It is available as a mixture of 3,6-diaminoacridinium chloride (35%) and its 10-metho-chloride (65%). [See Albert, The Acridines Arnold Press p 346 1966, Benda Chem Ber 45 1787 1912]. [Beilstein 23 I 650.] |
| Acriflavine hydrochloride Preparation Products And Raw materials |
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