Other grades of this product :
| 3-Aminoacetophenone Basic information |
| 3-Aminoacetophenone Chemical Properties |
| Melting point | 94-98 °C(lit.) | | Boiling point | 289-290 °C(lit.) | | density | 1.1031 (rough estimate) | | vapor pressure | 1.319Pa at 25℃ | | refractive index | 1.5700 (estimate) | | Fp | 289-291°C | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 3.41±0.10(Predicted) | | color | Yellow to light brown crystalline powder | | Water Solubility | 7.056g/L(37.5 ºC) | | Merck | 14,413 | | BRN | 386009 | | LogP | 0.83 | | CAS DataBase Reference | 99-03-6(CAS DataBase Reference) | | NIST Chemistry Reference | 3-Aminoacetophenone(99-03-6) | | EPA Substance Registry System | 3-Aminoacetophenone (99-03-6) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-36/37/38 | | Safety Statements | 36/37-36-26 | | WGK Germany | 2 | | RTECS | AM5800000 | | TSCA | T | | HazardClass | IRRITANT | | HS Code | 29223900 |
| 3-Aminoacetophenone Usage And Synthesis |
| Chemical Properties | 3-Aminoacetophenone is yellow to light brown crystalline powder
| | Uses | 3'-Aminoacetophenone has potential anti-bacterial properties in addition to being used in the synthesis of selective antagonists at human A2B adenosine receptors. As well, it is used in the synthesis
of HIV-1 Integrase Inhibitors. | | Uses | 3′-Aminoacetophenone (3-Acetylaniline) was used as reagent during the asymmetric total synthesis of pactamycin. It was used as starting reagent during the synthesis of curcumin mimics with substituted sulfonyl group. | | Synthesis Reference(s) | Synthetic Communications, 26, p. 973, 1996 DOI: 10.1080/00397919608003701 | | General Description | 3′-Aminoacetophenone acts as bifunctional coupling reagent during the synthesis of pyrimidines. | | Safety Profile | Moderately toxic by ingestion. Mddly toxic by skin contact. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NO,. See also AROMATIC AMINES. | | Purification Methods | Recrystallise it from EtOH or aqueous EtOH (m 99.5o). The thiosemicarbazone has m 202-204o (from EtOH). [Beilstein 14 H 45, 14 IV 96.] |
| 3-Aminoacetophenone Preparation Products And Raw materials |
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