Gestodene

Gestodene
  • CAS No.:60282-87-3
Other grades of this product :
Gestodene Basic information
Product Name:Gestodene
Synonyms:(8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14-decahydrocyclopenta[a]phenanthren-3-one;17-alpha-Ethynyl-13-ethyl-17-beta-hydroxy-4,15-gonadien-3-one;18,19-Dinorpregna-4,15-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17-alpha);(17R)-13-Ethyl-17-hydroxy-18,19-dinorpregna-4,15-dien-20-yn-3-one;15-ethyl-14-ethynyl-14-hydroxytetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-6,12-dien-5-one;Gestodene Methyl analogue: 17alpha-(1-Propyn-1-yl)-17a-hydroxy-18-Methyl-4,15-estradien-3-one;(8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,17-decahydro-1H-cyclopenta[a]phenanthren-3(2H)-one;(8R,9S,10R,13S,14S,17S)-13-ethyl-17-ethynyl-17-hydroxy-1,7,8,10,11,12,13,17-octahydro-2H-cyclopenta[a]phenanthren-3(6H,9H,14H)-one
CAS:60282-87-3
MF:C21H26O2
MW:310.43
EINECS:262-145-8
Product Categories:Steroid and Hormone;Hormone Drugs;Miscellaneous Biochemicals;Hormone;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
Mol File:60282-87-3.mol
Gestodene Chemical Properties
Melting point 190-192°C
Boiling point 462.7±45.0 °C(Predicted)
density 1.15±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO: >20mg/mL
form powder
pka12.16±0.40(Predicted)
color white to off-white
optical activity[α]/D -175 to -195° (DCM)
λmax240nm(MeOH)(lit.)
Merck 14,4413
InChIKeySIGSPDASOTUPFS-XUDSTZEESA-N
CAS DataBase Reference60282-87-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 62
Safety Statements 36/37-24/25
WGK Germany 3
RTECS JF7956000
HS Code 29144000
Hazardous Substances Data60282-87-3(Hazardous Substances Data)
Gestodene Usage And Synthesis
DescriptionGestodene is a progestogen, recently launched in combination with ethinyl estradiol as an oral contraceptive.Gestodene is a steroid. It has a role as an estrogen.Gestodene, one of three new gonane progestins, is the most potent on a per weight basis in regard to progestational effects and has little or no estrogenic effect. In in vivo animal studies, gestodene also has less androgenic activity compared with progestins found in older combination oral contraceptive formulations.
Chemical PropertiesWhite Crystalline Solid
OriginatorSchering AG (W. Germany)
UsesGestodene is an orally active gestogen with a progesterone-like profile of activity. Gestodene is used in combination with estrogen as an oral contraceptive.
UsesOrally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.
UsesEstrogens and progestins are female hormones. They are produced by the body and are necessary for the normal sexual development of the female and for the regulation of the menstrual cycle during the childbearing years. Gestodene is a progestogen hormonal
Brand nameFemodene

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