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| 5-Methylisatin Basic information |
| 5-Methylisatin Chemical Properties |
| Melting point | 180 °C (dec.) (lit.) | | density | 1.301±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | methanol: soluble25mg/mL, clear to slightly hazy, orange to red | | pka | 10.42±0.20(Predicted) | | form | crystalline | | color | orange | | BRN | 123738 | | CAS DataBase Reference | 608-05-9(CAS DataBase Reference) | | NIST Chemistry Reference | 5-Methyl-2,3-indolinedione(608-05-9) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-24/25-36-26 | | WGK Germany | 3 | | RTECS | NL7939300 | | HazardClass | IRRITANT | | HS Code | 29337900 |
| 5-Methylisatin Usage And Synthesis |
| Chemical Properties | Red to brown powder or crystals | | Uses | Reactant for preparation of:- Antimycobacterial agents
- Promoters of central nervous system (CNS) depression in mice
- Inhibitors of TAK1 kinase
- Anti-human immunodeficiency virus (HIV) agent
- Potent herpes simplex virus (HSV) inhibitors
- Antimicrobial agents
- IKKβ inhibitors
- Potential drug to combat human immunodeficiency virus-tuberculosis (HIV-TB) coinfection
- Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors
- Antibacterial and anticancer agents
| | Uses | Reactant for preparation of:• ;Antimycobacterial agents1• ;Promoters of central nervous system (CNS) depression in mice2• ;Inhibitors of TAK1 kinase3• ;Anti-human immunodeficiency virus (HIV) agent4• ;Potent herpes simplex virus (HSV) inhibitors5• ;Antimicrobial agents6• ;IKKβ inhibitors7• ;Potential drug to combat human immunodeficiency virus-tuberculosis (HIV-TB) coinfection8• ;Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors9• ;Antibacterial and anticancer agents | | General Description | 5-Methylisatin is an inhibitor of atrial natriuretic peptide (ANP) receptor coupled with guanylyl cyclase (GC). |
| 5-Methylisatin Preparation Products And Raw materials |
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