Chlorfenapyr

Chlorfenapyr
  • CAS No.:122453-73-0
Other grades of this product :
Chlorfenapyr Basic information
Description Reference
Product Name:Chlorfenapyr
Synonyms:PIRATE;STALKER;4-BROMO-2-(4-CHLOROPHENYL)-1-(ETHOXYMETHYL)-5-(TRIFLUOROMETHYL)-1H-PYRROL-3-CARBONITRILE;4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-5-trifluoromethyl-1H-pyrrole-3-carbonitrile;4-bromo-2-(4-chlorophenyl)-1-ethoxymethyl-5-trifluoromethylpyrrole-3-carbonitrile;Alert;Citrex;Intrepid
CAS:122453-73-0
MF:C15H11BrClF3N2O
MW:407.61
EINECS:
Product Categories:INSECTICIDE;Fungicide
Mol File:122453-73-0.mol
Chlorfenapyr Chemical Properties
Melting point 91-92°
Boiling point 443.5±45.0 °C(Predicted)
density 1.53±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
Water Solubility Insoluble in water
pka-18.00±0.70(Predicted)
form neat
color White to Almost white
BRN 6940152
InChIKeyCWFOCCVIPCEQCK-UHFFFAOYSA-N
CAS DataBase Reference122453-73-0(CAS DataBase Reference)
NIST Chemistry ReferenceChlorfenapyr(122453-73-0)
EPA Substance Registry SystemChlorfenapyr (122453-73-0)
Safety Information
Hazard Codes T;N,N,T
Risk Statements 22-23-50/53
Safety Statements 13-36/37-45-60-61
RIDADR UN 2811
WGK Germany 3
Hazardous Substances Data122453-73-0(Hazardous Substances Data)
ToxicityLD50 (single dose) in male, female rats (mg/kg): 223, 459 orally; in rabbits: >2000 dermally (Lovell); LC50 in Japanese carp: 0.5 ppm (Lovell)
MSDS Information
ProviderLanguage
Chlorfenapyr English
Chlorfenapyr Usage And Synthesis
DescriptionChlorfenapyr is a broad spectrum pesticide which is not approved for use in the EU, and only approved for limited applications in the US (applications for ornamental plants in greenhouses). It was originally rejected for FDA approval due to avian and aquatic toxicity. Data on human toxicity is still scarce, but it has moderate mammalian toxicity when taken orally, causing vacuolation of the nervous system in mice and rats. It is not persistent in ecosystems, and has low aqueous solubility. Chlorfenapyr can also be used as an insect-proofing agent in wool, and has been investigated for applications in malaria control.
Referencehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039634/ https://www3.epa.gov/pesticides/chem_search/reg_actions/registration/fs_PC-129093_01-Jan-01.pdf https://sitem.herts.ac.uk/aeru/ppdb/en/Reports/136.htm https://en.wikipedia.org/wiki/Chlorfenapyr https://www.pwrc.usgs.gov/resshow/Albers/albers1.htm
DescriptionChlorfenapyr is a pyrrole pro-insecticide that is metabolized in vivo into CL 303268 by mixed function oxidases. Chlorfenapyr increases respiratory activity in German cockroaches when used at concentrations ranging from 1 to 10 μg per insect but has no effect on respiration in Sf9 cells when used at concentrations ranging from 1 to 100 μM and does not affect respiration in isolated rat liver mitochondria up to a concentration of 10 μM. Chlorfenapyr is active against a variety of insects including those susceptible and resistant to pyrethroid and organophosphate insecticides, including horn flies (H. irritans) as well as A. culicifacies and A. stephensi mosquitos that carry malaria (LC50s = 2-2.39% suspension impregnated on paper). Chlorfenapyr is lethal to rats with LD50 values of 441 and 1,152 mg/kg for male and female rats, respectively. Formulations containing chlorfenapyr have been used to control termites and in agriculture to control various insects.
Chemical PropertiesOff-White Solid
UsesChlorfenapyr is a halogenated pyrrole based pro-insecticide. Chlorfenapyr functions by metabolizing into an active insecticide after entering the host. Chlorfenapyr is used primarily as a means of pes t control on cotton.
UsesInsecticide. Acaricide.
HazardA poison by ingestion. Moderately toxic by inhalation.
Agricultural UsesAcaracide, Insecticide, Miticide: Severely Restricted for use in EU. Active in U.S. as a foliar spray in greenhouses for ornamental crops and target pests including mites, caterpillar pests, thrips, and fungus gnats. No food use in U.S. Used on ornamental crops in commercial greenhouses to control mites, caterpillar pests, thrips and fungus gnats. Not for food use. Not an approved substance in EU countries. Registered for use in the U.S.
Trade nameAC 303630®; CL 303630®; PHANTOM®; PIRATE® 3 F; PYLON®; SUMILARV® chlorfenapyr Chemical class: Pyrrole (Pyrazole); Organofluorine

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