4-(METHYLSULFONYL)PHENYLBORONIC ACID

4-(METHYLSULFONYL)PHENYLBORONIC ACID
  • CAS No.:149104-88-1
Other grades of this product :
4-(METHYLSULFONYL)PHENYLBORONIC ACID Basic information
Product Name:4-(METHYLSULFONYL)PHENYLBORONIC ACID
Synonyms:(4-methanesulfonylphenyl)boranediol;4-(Methylsulfonyl)phenylboronic acid ,98%;4-methylfulfonylphenylboronic acid;4-[(Dioxo-lambda~6~-sulfanyl)methyl]phenylboronic acid;4-Boronophenyl methyl sulphone~4-(Methylsulphonyl)phenylboronic acid;4-(methylsulfonyloxy)phenylboronic acid;4-(Methylsulphonyl)benzeneboronic acid;4-Boronophenylmethylsulfone
CAS:149104-88-1
MF:C7H9BO4S
MW:200.02
EINECS:677-559-8
Product Categories:Boronate Ester;Potassium Trifluoroborate;Aryl;B (Classes of Boron Compounds);Boronic Acids & Esters;Phenyls & Phenyl-Het;blocks;BoronicAcids;Boronic Acids & Esters;Phenyls & Phenyl-Het;Boronic acids;Boronic Acid;Organoborons;Sulfonyl
Mol File:149104-88-1.mol
4-(METHYLSULFONYL)PHENYLBORONIC ACID Chemical Properties
Melting point 275-277 °C
Boiling point 445.5±51.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
pka7.22±0.10(Predicted)
form Powder
color Off-white
CAS DataBase Reference149104-88-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26-24/25-22
WGK Germany 3
HazardClass IRRITANT
HS Code 29163990
MSDS Information
ProviderLanguage
ACROS English
ALFA English
4-(METHYLSULFONYL)PHENYLBORONIC ACID Usage And Synthesis
Chemical PropertiesOff-white powder
Usessuzuki reaction
Uses4-(Methylsulfonyl)phenylboronic Acid is a heteroaryl boronic acid that was tested for their in vitro hormone-sensitive lipase inhibitory properties.
Uses4-(Methanesulfonyl)phenylboronic acid may be used as reagent for:
  • sequential Suzuki cross-coupling reactions
  • Copper-catalyzed oxidative trifluoromethylthiolation of aryl boronic acids
  • directed metalation and regioselective functionalization of 3-bromofuran and related heterocycles
  • Barton-Zard pyrrole cyclocondensations and Baeyer-Villiger oxidations
  • diplar cycloaddition and palladium-catalyzed cross-coupling processes
  • continuous flow Suzuki reactions for odanacatib intermediate synthesis
Reagent used in Preparation of
  • diarylaminopyridines as potential anti-malarial agents
  • hydropyranopyrazine via chloropyrazinecarboxaldehyde and olefination
  • biaryl sulfone derivatives as antagonists of the histamine H3 receptor
  • novel kinase inhibitor scaffolds with potential antitumor effects
  • Hepatitis C virus inhibition activity of N-hydroxyisoquinoline di
General DescriptionContains varying amounts of anhydride
4-(METHYLSULFONYL)PHENYLBORONIC ACID Preparation Products And Raw materials

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