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| Hyodeoxycholic acid Basic information |
| Hyodeoxycholic acid Chemical Properties |
| Melting point | 200-201 °C (lit.) | | alpha | D20 +8° (alc) | | Boiling point | 437.26°C (rough estimate) | | density | 0.9985 (rough estimate) | | refractive index | 1.4460 (estimate) | | storage temp. | Refrigerator | | solubility | Solubility in methanol, very faint turbidity. Slightly soluble in alcohol, acetone, ether and very slightly soluble in chloroform. | | pka | 4.76±0.10(Predicted) | | form | Solid | | color | White to Off-White | | Water Solubility | 5.889mg/L(25 ºC) | | Merck | 14,4857 | | InChIKey | DGABKXLVXPYZII-SIBKNCMHSA-N | | CAS DataBase Reference | 83-49-8(CAS DataBase Reference) |
| Hyodeoxycholic acid Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Protected β-Hyodeoxycholic Acid (H998105), a potential bile acid metabolite. | | Uses | Labelled Hyodeoxycholic Acid. Unlabelled version is isolated from pig bile. Antitumor agent | | Uses | It is isolated from pig bile. Antitumor agent | | Uses | Labelled β-Hyodeoxycholic Acid | | Definition | ChEBI: A member of the class of 5beta-cholanic acids that is (5beta)-cholan-24-oic acid substituted by alpha-hydroxy groups at positions 3 and 6. | | General Description | Hyodeoxycholic acid is a naturally occurring secondary bile acid. It is produced by the gut flora in the small intestine. Hyodeoxycholic acid is obtained from chenodeoxycholic acid during enterohepatic circulation of bile in rats. | | Purification Methods | Crystallise -hyodeoxycholic acid from EtOAc or Me2CO. The K salt separates in needles from an alcoholic solution of the acid when an equivalent of KOMe is added (see lithocholic acid). [Weiland & Gumlish Hoppe Seyler's Z Physiol Chem 215 18 1933, Windaus & Bohne Justus Liebigs Ann Chem 433 278 1923, Beilstein 10 III 1631.] |
| Hyodeoxycholic acid Preparation Products And Raw materials |
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