2-Cyano-3,5-difluoropyridine

CAS No.：298709-29-2

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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2-Cyano-3,5-difluoropyridine Basic information

Appearance

Product Name:	2-Cyano-3,5-difluoropyridine
Synonyms:	3,5-Difluoropicolinitrile;3,5-Difluoropyridine-2-carbonitrile;3,5-DIFLURO-2-CYANOPYRIDINE;2-Pyridinecarbonitrile,3,5-difluoro-(9CI);2-Cyano-3,5-difluoropyridine, 3,5-Difluoropicolinonitrile;3,5-DIFLUORO-2-PYRIDINECARBONITRILE;2-Cyano-3,5-difluorpyridine;3,5-difluoronicotinonitrile
CAS:	298709-29-2
MF:	C6H2F2N2
MW:	140.09
EINECS:	678-766-6
Product Categories:	Pyridine series;Pyridines;HALIDE;PYRIDINE;NITRILE;API intermediates;Fluorine series
Mol File:	298709-29-2.mol

2-Cyano-3,5-difluoropyridine Chemical Properties

Melting point	32-34°C
Boiling point	187.8±35.0 °C(Predicted)
density	1.36±0.1 g/cm3(Predicted)
Fp	90℃
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	-5.16±0.20(Predicted)
form	powder to crystal
color	White to Orange to Green
InChIKey	WLBIFECTHKFYKV-UHFFFAOYSA-N
CAS DataBase Reference	298709-29-2(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	20/21/22-36/38-41-37/38-22
Safety Statements	26-36/37/39-39
RIDADR	3276
WGK Germany	3
Hazard Note	Harmful/Irritant
HazardClass	6.1
PackingGroup	III
HS Code	2933399990

MSDS Information

Provider	Language
ALFA	English

2-Cyano-3,5-difluoropyridine Usage And Synthesis

Appearance	2-Cyano-3,5-difluoropyridine is a white to Orange to Green powder to crystal.
Uses	2-Cyano-3,5-difluoropyridine is a versatile reactant used in the preparation of potent and selective inhibitors of DPP-4 that exhibit an attractive pharmacokinetic profile as antidiabetics.

2-Cyano-3,5-difluoropyridine Preparation Products And Raw materials

Preparation Products

1-(3,5-difluoropyridin-2-yl)ethanone-->3,5-Difluoropicolinic acid

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