Other grades of this product :
| ASARININ Basic information |
| Product Name: | ASARININ | | Synonyms: | (-)-SESAMINE;(-)-ASARININ;ASARININ;EPI-SESAMIN;(-)-5,5'-[(1R,3aα,4S,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[1,3-benzodioxole];5,5'-[(1R,3aα,4S,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(1,3-benzodioxole);L-Asarinin;5-[4-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-1-yl]-1,3-benzodioxole | | CAS: | 133-04-0 | | MF: | C20H18O6 | | MW: | 354.35 | | EINECS: | | Product Categories: | Lichen Products | | Mol File: | 133-04-0.mol |
| ASARININ Chemical Properties |
| Melting point | 121° | | alpha | D20 -118.6°; D23 -122° (chloroform) | | Boiling point | 504.4±50.0 °C(Predicted) | | density | 1.385±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), DMSO (Slightly, Sonicated) | | form | Solid | | color | White to Off-White |
| ASARININ Usage And Synthesis |
| Description | Asarinin is a lignan that has been found in A. sieboldii. It is an epimer of sesamin and a noncompetitive inhibitor of Δ5-desaturase (Ki = 0.28 mM). It is selective for Δ5-desaturase over Δ6- and Δ9-desaturase. Asarinin is cytotoxic to A2780 and SKOV3 ovarian cancer cells (IC50s = 38.45 and 60.87 μM, respectively) but not immortalized ovarian surface epithelial cells (IC50 = >200 μM). It induces apoptosis and activates caspase-3, -8, and -9 in A2780 and SKOV3 cells. | | Uses | l-Asarinin in combination with pellitorine is a potential larvicides for the control of insecticide-resistant mosquito populations. Possesses antimicrobial activity. |
| ASARININ Preparation Products And Raw materials |
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