4-Fluoro-3-(trifluoromethyl)aniline

CAS No.：2357-47-3

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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4-Fluoro-3-(trifluoromethyl)aniline Basic information

Product Name:	4-Fluoro-3-(trifluoromethyl)aniline
Synonyms:	α,α,α,4-Tetrafluoro-m-toluidine;5-Amino-2-fluorobenzotrifluoride, α,α,α,4-Tetrafluoro-m-toluidine;Benzenamine, 4-fluoro-3-(trifluoromethyl)-;4-Fluoro-3-(trifluoromethyl)-1-benzenamine;alpha,alpha,alpha,4-Tetrafluoro-m-toluidine,99%;2-Fluoro-2-aminobenzotrifluoride;4-Fluoro-3-trifluoromethyl-phenylamine;2-Fluoro-5-Aminotrifluoromethylbenzene
CAS:	2357-47-3
MF:	C7H5F4N
MW:	179.11
EINECS:	219-095-7
Product Categories:	Fluorobenzene;Anilines, Aromatic Amines and Nitro Compounds;Amines;Aromatic Halides (substituted);Aniline;API intermediates;Trifluoromethylbenzene serise;blocks;FluoroCompounds;Miscellaneous
Mol File:	2357-47-3.mol

4-Fluoro-3-(trifluoromethyl)aniline Chemical Properties

Boiling point	207-208 °C (lit.)
density	1.393 g/mL at 25 °C (lit.)
refractive index	n20/D 1.466(lit.)
Fp	197 °F
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Oil
pka	3.43±0.10(Predicted)
color	Colourless
Specific Gravity	1.41
BRN	641587
InChIKey	PGFQDLOMDIBAPY-UHFFFAOYSA-N
CAS DataBase Reference	2357-47-3(CAS DataBase Reference)
NIST Chemistry Reference	Benzenamine, 4-fluoro-3-(trifluoromethyl)-(2357-47-3)

Safety Information

Hazard Codes	Xn,Xi,T
Risk Statements	20/21/22-36/37/38-23-21/22
Safety Statements	26-36-45-36/37/39
RIDADR	2811
WGK Germany	3
Hazard Note	Irritant
HazardClass	6.1
HS Code	29214300

MSDS Information

Provider	Language
5-Amino-2-fluorobenzotrifluoride	English
SigmaAldrich	English
ACROS	English
ALFA	English

4-Fluoro-3-(trifluoromethyl)aniline Usage And Synthesis

Chemical Properties	clear yellow to brown-red liquid
Uses	4-Fluoro-3-(trifluoromethyl)aniline was used in the synthesis of well-defined rod-coil block copolymers of trifluoromethylated poly(phenylene oxide).

4-Fluoro-3-(trifluoromethyl)aniline Preparation Products And Raw materials

Preparation Products

5-[4-FLUORO-3-(TRIFLUOROMETHYL)PHENYL]-2-FURALDEHYDE

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