(S)-(+)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate

CAS No.：35193-64-7

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(S)-(+)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate Basic information

Reaction

Product Name:	(S)-(+)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate
Synonyms:	(S)-(+)-BNP ACID;(S)-(+)-BNPA;(S)-(+)-BPA;(S)-4-HYDROXY DINAPHTHO[2,1-D:1',2'-F][1,3,2]-DIOXAPHOPHEPIN-4-OXID;(S)-4-HYDROXYDINAPHTHO[2,1-D:1',2'-F][1,3,2]DIOXAPHOSPHEPIN-4-OXIDE;(S)-(+)-1,1'-BINAPHTHELENE-2,2'-DIYL-PHOSPHATE;(S)-(+)-1,1'-BINAPHTHYL-2,2'-DIYL HYDROGENPHOSPHATE;S-1,1'-BINAPHTHYL-2,2'-DIYL HYDROGENPHOSPHATE
CAS:	35193-64-7
MF:	C20H13O4P
MW:	348.29
EINECS:
Product Categories:	Chiral Compound;Analytical Chemistry;e.e. / Absolute Configuration Determination (NMR);Enantiomer Excess & Absolute Configuration Determination;for Resolution of Bases;Optical Resolution;Chiral Compounds;chiral;API intermediates;Synthetic Organic Chemistry;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Phosphine;bc0001
Mol File:	35193-64-7.mol

(S)-(+)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate Chemical Properties

Melting point	≥300 °C
alpha	607.5 º (c=1.4,MeOH)
Boiling point	619.5±38.0 °C(Predicted)
density	1.49±0.1 g/cm3(Predicted)
refractive index	595 ° (C=1, MeOH)
storage temp.	Sealed in dry,Room Temperature
solubility	Soluble in DMSO and methanol (hot).
form	Powder
pka	1.14±0.20(Predicted)
color	white
optical activity	[α]22/D +595°, c = 1.35 in methanol
BRN	4787775
CAS DataBase Reference	35193-64-7(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/21/22
Safety Statements	26-36-36/37/39-22
WGK Germany	3
RTECS	RZ2475100
F	10-23
HS Code	29199000

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

(S)-(+)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate Usage And Synthesis

Reaction	Asymmetric hetero Diels-Alder reaction catalyzed by chiral lanthanide(III) complex. Highly efficient Mannich reaction Acidic Resolving agent for certain amine/racemic mixtures.
Chemical Properties	white to light yellow crystal powde
Uses	The S enantiomer of binaphthol derivative as chiral quenching agent.
Uses	Used as a chiral Bronsted acid catalyst in the enantoselective Mannich reaction.
Purification Methods	Recrystallise it from EtOH. Reflux for 3hours in N NaOH is required to hydrolyse the cyclic phosphate. [Jacques et al. Tetrahedron Lett 4617 1971, Arnold et al. Tetrahedron 24, 343 1983.]

(S)-(+)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate Preparation Products And Raw materials

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