Loxoprofen sodium

Loxoprofen sodium
  • CAS No.:80382-23-6
Other grades of this product :
Loxoprofen sodium Basic information
Product Name:Loxoprofen sodium
Synonyms:alpha-methyl-4-((2-oxocyclopentyl)methyl)benzeneacetatesodiumsaltdihydrate;benzeneaceticacid,alpha-methyl-4-((2-oxocyclopentyl)methyl)-,sodiumsalt,di;cs-600;loxoprofensodium(patented-nosupply);Loxoprofen sodium dihydrate, >=99%;Sodium 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate;sodium 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoate dihydrate;2-{4-[(2-Oxocyclopentyl)methyl]phenyl}propanoic acid sodium salt
CAS:80382-23-6
MF:C15H19NaO3
MW:270.3
EINECS:1806241-263-5
Product Categories:Analgesics;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Antipyretic analgesics;APIS;Other APIs
Mol File:80382-23-6.mol
Loxoprofen sodium Chemical Properties
storage temp. Inert atmosphere,Room Temperature
CAS DataBase Reference80382-23-6(CAS DataBase Reference)
Safety Information
MSDS Information
Loxoprofen sodium Usage And Synthesis
DescriptionLoxoprofen sodium i s an antiinflammatory/analgesic agent useful in the management of rheumatoid arthritis and related disorders. It is converted in vivo to the corresponding trans-hydroxycyclopentane analog, through which it appears to exert its activity.
OriginatorSankyo (Japan)
Usesanti-inflammatory
DefinitionChEBI: A hydrate that is the dihydrate form of loxoprofen sodium. The parent acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol metabolite following oral administration.
Brand nameLOXONIN
Mechanism of actionAs most NSAIDs, loxoprofen is a non-selective cyclooxygenase inhibitor, and works by reducing the synthesis of prostaglandins from arachidonic acid.
Side effectsAdverse effects include anorexia, nausea, vomiting, bleeding, anemia, diarrhea, and constipation.
Loxoprofen sodium Preparation Products And Raw materials

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