2-Tolylboronic acid

2-Tolylboronic acid
  • CAS No.:16419-60-6
Other grades of this product :
2-Tolylboronic acid Basic information
Description
Product Name:2-Tolylboronic acid
Synonyms:AKOS BRN-0017;2-METHYLPHENYLBORONIC ACID;2-METHYLBENZENEBORONIC ACID;2-TOLYLBORONIC ACID;TOLUENE-2-BORONIC ACID;O-TOLYLBORONIC ACID;O-METHYLPHENYLBORONIC ACID;o-Tolylboronic acid, 2-Boronotoluene
CAS:16419-60-6
MF:C7H9BO2
MW:135.96
EINECS:605-351-9
Product Categories:Substituted Boronic Acids;organic or inorganic borate;blocks;BoronicAcids;Boronic Acid series;Boron, Nitrile, Thio,& TM-Cpds;Boronic Acid;Aryl;Organoborons;B (Classes of Boron Compounds);Boronic Acids;CHIRAL CHEMICALS;Boronate Ester;Potassium Trifluoroborate
Mol File:16419-60-6.mol
2-Tolylboronic acid Chemical Properties
Melting point 162-164 °C(lit.)
Boiling point 283.4±33.0 °C(Predicted)
density 1.10±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka8.61±0.58(Predicted)
form Crystalline Powder
color Beige
Water Solubility Slightly soluble in water.
BRN 2935796
InChIKeyNSJVYHOPHZMZPN-UHFFFAOYSA-N
CAS DataBase Reference16419-60-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS ED7777777
HazardClass IRRITANT
HS Code 29163990
MSDS Information
ProviderLanguage
2-Tolylboronic acid English
ACROS English
SigmaAldrich English
ALFA English
2-Tolylboronic acid Usage And Synthesis
Description2-Methylphenylboronic acid is an important organic boronic acid compound, which is widely used in Suzuki cross-coupling reaction and has important application value in the fields of organic synthesis and medicine and chemical industry.
Physical propertiesbeige crystalline powder
Usessuzuki reaction
Uses2-Methylbenzeneboronic acid is a reagent used for Pd-catalyzed arylation using Suzuki-Miyaura cross-coupling in water, Ruthenium catalyzed direct arylation reactions, Ligand-free copper-catalyzed coupling reactions, Rhodium-catalyzed asymmetric 1,4-addition reactions. Reagent used in Preparation of chiral monophosphorus ligands in asymmetric Suzuki-Miyaura coupling reaction, Human farnesyl pyrophosphate synthase inhibitors as antitumor agents for multiple myeloma cells

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