Boc-O-tert-butyl-L-threonine

CAS No.：13734-40-2

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Boc-O-tert-butyl-L-threonine Basic information

Product Name:	Boc-O-tert-butyl-L-threonine
Synonyms:	N-ALPHA-T-BUTOXYCARBONYL-O-T-BUTYL-L-THREONINE;N-ALPHA-TERT-BUTYLOXYCARBONYL-O-TERT-BUTYL-L-THREONINE;N-ALPHA-T-BOC-O-T-BUTYL-L-THREONINE;BOC-O-T-BUTYL-L-THREONINE;BOC-O-TERT-BUTYL-L-THREONINE;BOC-L-THR(TBU)-OH;BOC-THREONINE(TBU)-OH;BOC-THR(BUT)-OH
CAS:	13734-40-2
MF:	C13H25NO5
MW:	275.34
EINECS:
Product Categories:	Amino Acids;Threonine [Thr, T];Boc-Amino Acids and Derivative;Boc-Amino acid series
Mol File:	13734-40-2.mol

Boc-O-tert-butyl-L-threonine Chemical Properties

Melting point	95-98 °C
Boiling point	391.3±37.0 °C(Predicted)
density	1.070±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in DMF.
form	Solid
pka	3.53±0.10(Predicted)
optical activity	[α]20/D +3.6±0.5°, c = 2% in DMF
BRN	4454820
CAS DataBase Reference	13734-40-2(CAS DataBase Reference)

Safety Information

WGK Germany	3
HS Code	2924 19 00

MSDS Information

Provider	Language
SigmaAldrich	English

Boc-O-tert-butyl-L-threonine Usage And Synthesis

Uses	N-Boc-O-tert-butyl-L-threonine is used as pharmaceutical intermediate.
General Description	Boc-Thr(t-Bu)-OH (N-Boc-O-tert-butyl-L-threonine) participates in the synthesis of 2,3-unsaturated glycosides, via reaction with per-O-acetylated glucal in the presence of Er(OTf)₃ catalyst.

Boc-O-tert-butyl-L-threonine Preparation Products And Raw materials

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