| 2-[1-PIPERAZINYL]QUINOLINE MALEATE SALT Basic information |
| Product Name: | 2-[1-PIPERAZINYL]QUINOLINE MALEATE SALT |
| Synonyms: | 1-(2-quinolyl)piperazinemaleate;2-(1-piperazinyl)-quinolin(z)-2-butenedioate(1:1);2-(1-piperazinyl)quinoline(z)-2-butenedioate(1:1);2-(1-piperazinyl)-quinolinmaleate(1:1);ma1291;quipazinemeleate;2-(1-PIPERAZINYL)QUINOLINE DIMALEATE;2-[1-PIPERAZINYL]QUINOLINE MALEATE SALT |
| CAS: | 5786-68-5 |
| MF: | C17H19N3O4 |
| MW: | 329.35 |
| EINECS: | 227-314-2 |
| Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 5786-68-5.mol |
| 2-[1-PIPERAZINYL]QUINOLINE MALEATE SALT Chemical Properties |
| Melting point | 151-154℃ |
| storage temp. | 2-8°C |
| solubility | H2O: soluble |
| form | Solid |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | VC2515000 |
| HazardClass | 6.1 |
| MSDS Information |
| 2-[1-PIPERAZINYL]QUINOLINE MALEATE SALT Usage And Synthesis |
| Uses | Quipazine is a non-selective serotonin receptor agonist. Quipazine increases renin release by a peripheral hemodynamic mechanism. |
| Uses | Selective 5-HT-3 receptor agonist |
| Uses | Quipazine maleate salt has been used as a serotonin receptor agonist to study its effects on mouse models with spinal cord injury. It has also been used as a serotonin receptor agonist to study its effects on the locomotion of zebrafish. |
| Biological Activity | Selective 5-HT 3 receptor agonist. Also displays antagonist activity at peripheral 5-HT 3 receptors. [ 3 H]-Quipazine labels 5-HT 3 sites in the cortical membranes. |
| Biochem/physiol Actions | Quipazine belongs to the class of psychedelics and acts as a serotonin/5-hydroxytryptamine-2A/C receptor agonist. It also acts as an inhibitor of prolactin. |
| 2-[1-PIPERAZINYL]QUINOLINE MALEATE SALT Preparation Products And Raw materials |
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