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| METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE Basic information |
| METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE Chemical Properties |
| Melting point | 160-163 °C(lit.) | | Boiling point | 261.15°C (rough estimate) | | density | 1.5918 (rough estimate) | | refractive index | 1.5820 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Chloroform, Ethanol, Ether, Ethyl Acetate, Methanol | | form | Powder | | pka | 11.25±0.40(Predicted) | | color | Light Yellow | | InChIKey | BBFWUUBQSXVHHZ-UHFFFAOYSA-N | | CAS DataBase Reference | 10068-07-2(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29349990 |
| METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE Usage And Synthesis |
| Chemical Properties | Light Yellow Powder | | Uses | An interesting intermediate | | Uses | Methyl 3-hydroxy-5-isoxazolecarboxylate was used in the enantioselective synthesis of a key precursor to the tetracycline antibiotics. It was also used in the preparation of formamidinopiperidine analog, an N-amidinopiperidine compound. | | Synthesis Reference(s) | Journal of Medicinal Chemistry, 20, p. 965, 1977 DOI: 10.1021/jm00217a023 |
| METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE Preparation Products And Raw materials |
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