N-METHYLACETANILIDE

CAS No.：579-10-2

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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N-METHYLACETANILIDE Basic information

Product Name:	N-METHYLACETANILIDE
Synonyms:	Acetanilide, N-methyl-;Acetomethylanilide;aceto-n-methylanilide;Exalgin;Methylantifebrin;Methylazol;N-Acetyl-N-methylaniline;n-methyl-acetanilid
CAS:	579-10-2
MF:	C9H11NO
MW:	149.19
EINECS:	209-436-8
Product Categories:
Mol File:	579-10-2.mol

N-METHYLACETANILIDE Chemical Properties

Melting point	101°C
Boiling point	146 °C / 30mmHg
density	1.0036
refractive index	1.5760
storage temp.	Sealed in dry,Room Temperature
pka	0.54±0.50(Predicted)
form	powder to crystal
color	White to Almost white
Water Solubility	24.96g/L(25 ºC)
CAS DataBase Reference	579-10-2(CAS DataBase Reference)
EPA Substance Registry System	Acetamide, N-methyl-N-phenyl- (579-10-2)

Safety Information

Hazard Codes	T
Risk Statements	36/37/38-25
Safety Statements	26-36/37/39-45-24/25
RIDADR	UN 2811 6.1/PG 3
RTECS	AE4900000
HazardClass	6.1
PackingGroup	III
HS Code	29242990

MSDS Information

N-METHYLACETANILIDE Usage And Synthesis

Synthesis Reference(s)	The Journal of Organic Chemistry, 14, p. 1099, 1949 DOI: 10.1021/jo01158a020
Purification Methods	Crystallise the anilide from water, ether, pet ether (b 80-100o) or *C6H6 (m 105o). The BF3 salt has m 114o (from Me2CO/diisopropyl ether). [Beilstein 12 III 465, 12 IV 378.]

N-METHYLACETANILIDE Preparation Products And Raw materials

Raw materials	4,4'-Methylenebis(N,N-dimethylaniline)-->Acetic acid-->N,N-Dimethylaniline
Preparation Products	Mefenacet-->1-METHYL-2-INDOLINONE

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