Calcium folinatc

Calcium folinatc
  • CAS No.:6035-45-6
Other grades of this product :
Calcium folinatc Basic information
Product Name:Calcium folinatc
Synonyms:calcium 2-[[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]phenyl]-oxomethyl]amino]pentanedioate pentahydrate;FOLINIC ACID CALCIUM CELL CULTURE TESTED;Folinic acid, calcium salt pentahydrate, 95.0-105.0%;Calcium folinatc;Folinic acid calcium salt;Leucovorin calcium pentahydrate;NSC-3590;CALCIUM FOLINATE(FOLINIC ACID)(RG)
CAS:6035-45-6
MF:C20H27CaN7O8
MW:533.56
EINECS:
Product Categories:API;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Calcium, Calcium Folinatc, Citrovorum Factor;Miscellaneous Biochemicals
Mol File:6035-45-6.mol
Calcium folinatc Chemical Properties
Melting point 240-250°C
alpha D21 +14.9° (c = 1 in water)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility insoluble in DMSO; insoluble in EtOH; ≥15.04 mg/mL in H2O with gentle warming
form powder
color Yellow-white to yellow
Safety Information
Hazard Codes Xn
Risk Statements 36/37/38-42/43
Safety Statements 26-36
WGK Germany 3
HS Code 29362900
MSDS Information
Calcium folinatc Usage And Synthesis
Chemical Propertiesyellowish-white to yellow powder
UsesAn intermediate product of the metabolism of Folic Acid. This compound is a mixture of diastereomers.
UsesAntianemic
Brand nameWellcovorin (GlaxoSmithKline).
Biological Activityhuman lymphoid cell lines were studied for leucovorin requirements to protect from methotrexate (mtx)-induced growth suppression. over a 72h continuous exposure leucovorin provided better protection to the cell lines laz-007 and raji than to the cell line
Calcium folinatc Preparation Products And Raw materials

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