COLISTIMETHATE SODIUM

COLISTIMETHATE SODIUM
  • CAS No.:8068-37-9
Other grades of this product :
COLISTIMETHATE SODIUM Basic information
Product Name:COLISTIMETHATE SODIUM
Synonyms:COLISTIMETHATE SODIUM;ColistinSulphomethate;Colimicina;Colimyscine;COLISTIMETHATE SODIUM USP/EP/BP
CAS:8068-37-9
MF:C58H105N16Na5O28S5
MW:0
EINECS:
Product Categories:
Mol File:Mol File
COLISTIMETHATE SODIUM Chemical Properties
Safety Information
MSDS Information
COLISTIMETHATE SODIUM Usage And Synthesis
UsesAntibacterial.
Brand nameColy-Mycin (Monarch).
General DescriptionIn colistin, five of the terminal amino groups of the α-aminobutyric acid fragment may be readily alkylated. In colistimethatesodium, pentasodium colistinmethanesulfonate,sodium colistimethanesulfonate (Coly-Mycin M), the methanesulfonate radical is the attached alkyl group, and asodium salt may be made through each sulfonate. This providesa highly water-soluble compound that is very suitablefor injection. In the injectable form, it is given intramuscularlyand is surprisingly free from toxic reactions comparedwith polymyxin B. Colistimethate sodium does not readilyinduce the development of resistant strains of microorganisms,and there is no evidence of cross-resistance with thecommon broad-spectrum antibiotics. It is used for the sameconditions mentioned for colistin.
COLISTIMETHATE SODIUM Preparation Products And Raw materials

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