Other grades of this product :
| Iron saccharate Basic information |
| Iron saccharate Chemical Properties |
| HS Code | 29400090 | | Toxicity | LD50 in mice (mg Fe/kg): >2500 orally; >200 i.v. (Geisser) |
| Iron saccharate Usage And Synthesis |
| Chemical Properties | Brown solid | | Uses | Semi-synthetic macrolide antibiotic | | Uses | Iron Saccharate has been used to treat iron deficiency and iron deficiency anemia associated with different chronic diseases. | | Brand name | Venofer (Luitpold). | | Clinical Use | Phosphate binder | | Drug interactions | Potentially hazardous interactions with other drugs
Antibacterials: reduced absorption of 4-quinolones
and tetracyclines.
Dimercaprol: avoid concomitant use.
Mycophenolate: may significantly reduce absorption
of mycophenolate. | | Metabolism | After intravenous infusion, iron sucrose is taken up by
the cells of the reticuloendothelial cells, particularly in the
liver and spleen. The reticuloendothelial cells gradually
separate iron from the iron-sucrose complex. Most
absorbed iron is bound to transferrin and transported
to the bone marrow where it is incorporated into
haemoglobin; the remainder is contained within the
storage forms, ferritin or haemosiderin, or as myoglobin,
with smaller amounts occurring in haem-containing
enzymes or in plasma bound to transferrin.
Only very small amounts of iron are excreted as the
majority released after the destruction of the haemoglobin
molecule is re-used. |
| Iron saccharate Preparation Products And Raw materials |
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