Product

4-Piperidinemethanol

CAS No.：6457-49-4

Other grades of this product :

4-Piperidinemethanol Basic information

Product Name:	4-Piperidinemethanol
Synonyms:	4-(Hydroxymethyl)piperidine, 98 % (NMR+TLC);Piperidine-4-methanol;4-Piperidinemethanol ,98%;piperidin-4-ylmethanol hydrochloride;2-HydroMethyl piperidine;4-PiperidineMethanol, 98% 5GR;4-PiperidineMethanol or 4-(HydroxyMethyl)piperidine;PiperidineMethanol
CAS:	6457-49-4
MF:	C6H13NO
MW:	115.17
EINECS:	613-624-9
Product Categories:	Piperidine Series;Pyrans, Piperidines & Piperazines;pharmacetical;PiperidineDerivative;Hydroxymethyl's;Alkohols;Alcohols and Derivatives;Amines and Anilines;Pyrans, Piperidines &Piperazines;Piperidine
Mol File:	6457-49-4.mol

4-Piperidinemethanol Chemical Properties

Melting point	55-59 °C(lit.)
Boiling point	118-120 °C10 mm Hg(lit.)
density	0,997 g/cm³
Fp	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Water Solubility	Soluble in water
form	Crystalline Powder, Chunks and/or Solid
pka	14.94±0.10(Predicted)
color	White to off-white
Sensitive	Hygroscopic
BRN	103071
InChIKey	XBXHCBLBYQEYTI-UHFFFAOYSA-N
CAS DataBase Reference	6457-49-4(CAS DataBase Reference)

Safety Information

Hazard Codes	C,Xi
Risk Statements	34-22
Safety Statements	26-27-36/37/39-45
RIDADR	UN 3263 8/PG 2
WGK Germany	3
Hazard Note	Irritant/Hygroscopic
HazardClass	8
PackingGroup	III
HS Code	29333990

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

4-Piperidinemethanol Usage And Synthesis

Chemical Properties	white to off-white crystalline powder, chunks
Uses	4-Piperidinemethanol may be used in the preparation of: N-tert-butoxycarbonyl-4-hydroxymethyl piperidine desferrioxamine B (DFO) containing third generation triazine dendrimer ethyl 3-(4-(hydroxymethyl)piperidin-1-yl)propanoate (EHMPP) 4-(hydroxymethyl)piperidine-1-carbodithioic acid (HL) 1-[[(1E)-2-(4-chlorophenyl)ethenyl]sulfonyl]-4-piperidinemethanol
General Description	4-Piperidinemethanol is a cyclic secondary amine. Its standard molar enthalpies of combustion, sublimation and formation have been determined.

4-Piperidinemethanol Preparation Products And Raw materials

Raw materials

2-Piperidinone, 4-(methoxymethyl)--->4-Methoxy-7-Morpholinobenzo[d]thiazol-2-aMine-->N-Boc-4-piperidinemethanol-->ETHYL 1-PIPERIDINECARBOXYLATE-->4-(METHOXYMETHYL)PIPERIDINE-->1-Iodoheptane

Preparation Products

1-Boc-4-(aminomethyl)piperidine-->Terfenadine-->(1-(4-(Hydroxymethyl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-yl)methanol-->(2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidin-5-yl)methanol-->2-(4-(Hydroxymethyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide-->2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxylate-->BENZYL 4-(BROMOMETHYL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE-->2-(4-(Hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxamide-->Ethyl 2-(4-(hydroxymethyl)piperidin-1-yl)pyrimidine-5-carboxylate-->2-(4-Chloromethylpiperidin-1-yl)pyrimidine-5-carboxamide ,97%-->Ethyl 2-(4-(hydroxymethyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate-->1-tert-Butoxycarbonyl-4-piperidinecarboxaldehyde

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