Trimethyl orthoacetate

Trimethyl orthoacetate
  • CAS No.:1445-45-0
Other grades of this product :
Trimethyl orthoacetate Basic information
Product Name:Trimethyl orthoacetate
Synonyms:1,1,1-trimethoxy-ethan;CH3C(OCH3)3;Methyl orthoacetate;trimethyl-acetate;Trimethylorthoaceate;ORTHOACETIC ACID TRIMETHYL ESTER;TMOA;TRIMETHYL ORTHOACETATE
CAS:1445-45-0
MF:C5H12O3
MW:120.15
EINECS:215-892-9
Product Categories:Organic synthesis;Acetals/Ketals/Ortho Esters;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Orthoesters
Mol File:1445-45-0.mol
Trimethyl orthoacetate Chemical Properties
Boiling point 107-109 °C(lit.)
density 0.944 g/mL at 25 °C(lit.)
vapor pressure 20 hPa (20 °C)
refractive index n20/D 1.388(lit.)
Fp 62 °F
storage temp. Store below +30°C.
form Liquid
color Clear colorless to slightly brown
Specific Gravity0.960 (20/4℃)
Water Solubility HYDROLYSIS
Sensitive Moisture Sensitive
BRN 1098338
InChIKeyHDPNBNXLBDFELL-UHFFFAOYSA-N
LogP1.13 at 25℃
CAS DataBase Reference1445-45-0(CAS DataBase Reference)
NIST Chemistry ReferenceEthane, 1,1,1-trimethoxy-(1445-45-0)
EPA Substance Registry SystemTrimethyl orthoacetate (1445-45-0)
Safety Information
Hazard Codes F,Xi
Risk Statements 11-43-38-36/37/38
Safety Statements 16-37/39-24-33-26-7/9
RIDADR UN 3272 3/PG 2
WGK Germany 1
TSCA Yes
HazardClass 3
PackingGroup II
HS Code 29159080
ToxicityLD50 orally in Rabbit: > 2000 mg/kg
MSDS Information
ProviderLanguage
Trimethyl orthoacetate English
SigmaAldrich English
ACROS English
ALFA English
Trimethyl orthoacetate Usage And Synthesis
Chemical PropertiesCLEAR COLOURLESS TO SLIGHTLY BROWN LIQUID
UsesTrimethyl orthoacetate has been used in the preparation of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-amino-9-(3-alkoxycarbonyl-oxymethyl-4-alkoxycarbonyloxybut -1-yl)purines.
General DescriptionKinetics and mechanism of gas-phase elimination of trimethyl orthoacetate has been examined over the temperature range of 310-369°C and pressure range of 50-130Torr.

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