| 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE Basic information |
| Product Name: | 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE |
| Synonyms: | 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE;1-(4-hydroxy-3-methoxyphenyl)-3-p-tolylpropan-2-one;1-(4-Hydroxy-3-methoxyphenyl)-3-(4-methylphenyl)propan-2-one;4-Hydroxy-3-Methoxy-4-Methylbenzophenone;(4-Hydroxy-3-Methoxyphenyl)(4-Methylphenyl)-Methanone;(4-hydroxy-3-methoxyphenyl)(p-tolyl)methanone;4-hydroxy-3-methoxy-4-methyl phenyl methanone;Methanone, (4-hydroxy-3-methoxyphenyl)(4-methylphenyl)- |
| CAS: | 134612-39-8 |
| MF: | C15H14O3 |
| MW: | 242.27 |
| EINECS: | |
| Product Categories: | Aromatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals |
| Mol File: | 134612-39-8.mol |
| 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE Chemical Properties |
| Melting point | 103–105°C |
| storage temp. | 2-8°C |
| solubility | Dichloromethane |
| form | Solid |
| color | Light Brown |
| Safety Information |
| MSDS Information |
| 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE Usage And Synthesis |
| Chemical Properties | Light Brown Solid |
| Uses | Intermediate in the preparation of Tolcapone (T535252) and its derivatives. |
| Uses | 4-Hydroxy-3-methoxy-4''-methylbenzophenone is used in the preparation of Tolcapone (T535252), a selective catechol-O-methyltransferase inhibitor. |
| Preparation | Preparation by reaction of 33% hydrobro mic acid in acetic acid with 4-(benzyloxy)- 3-methoxy-4′-methyl-benzophenone in methylene chloride at 20–25°. |
| 3-METHOXY-4-HYDROXYBENZYL,4'-METHYLBENZYL KETONE Preparation Products And Raw materials |
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