| Ethyl picolinate Basic information |
| Product Name: | Ethyl picolinate |
| Synonyms: | Pyridine-2-A Ethyl;Ethyl Picolinate Picolinic Acid Ethyl Ester Pyridine-2-carboxylic Acid Ethyl Ester;ETHYL 2-PYRIDINECARBOXYLATE FOR SYNTHESI;Ethyl picolinate, 99% 100ML;ETHYL PICOLINATE;ETHYL PYRIDINE-2-CARBOXYLATE;ETHYL 2-PYRIDINECARBOXYLATE;ETHYL 2-PICOLINATE |
| CAS: | 2524-52-9 |
| MF: | C8H9NO2 |
| MW: | 151.16 |
| EINECS: | 219-758-0 |
| Product Categories: | Aromatics;Heterocycles;CARBOXYLICESTER;GLYCINESCAFFOLD;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatic Esters;Acids & Esters;Miscellaneous Compounds |
| Mol File: | 2524-52-9.mol |
| Ethyl picolinate Chemical Properties |
| Melting point | 2 °C (lit.) |
| Boiling point | 240-241 °C (lit.) |
| density | 1.119 g/mL at 25 °C (lit.) |
| refractive index | n |
| Fp | 225 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Liquid |
| pka | 1.83±0.10(Predicted) |
| color | Clear yellow or pink |
| Water Solubility | miscible |
| BRN | 122485 |
| InChIKey | FQYYIPZPELSLDK-UHFFFAOYSA-N |
| CAS DataBase Reference | 2524-52-9(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Pyridinecarboxylic acid, ethyl ester(2524-52-9) |
| EPA Substance Registry System | Ethyl picolinate (2524-52-9) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29333999 |
| MSDS Information |
| Provider | Language |
|---|---|
| Ethyl pyridine-2-carboxylate | English |
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| Ethyl picolinate Usage And Synthesis |
| Chemical Properties | clear yellowish or pink liquid |
| Uses | Ethyl picolinate can be used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes. |
| Uses | Ethyl picolinate is used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors which is used in the treatment of diabetes. It is also used as pharmaceutical intermediate. |
| Synthesis Reference(s) | Chemical and Pharmaceutical Bulletin, 43, p. 1028, 1995 DOI: 10.1248/cpb.43.1028 |
| Ethyl picolinate Preparation Products And Raw materials |
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