6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE

6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE
  • CAS No.:1837-57-6
Other grades of this product :
6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Basic information
Product Name:6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE
Synonyms:2-ETHOXY-6,9-DIAMINOACRIDINE LACTATE;ACRINOL;6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE;ETHACRIDINE LACTATE;ETHODIN;ETHACRIDINELACTATE(2-ETHOXY-6,9-DIAMINOACRIDINELACTATEHYDRATE);ACRYNOL;Acrinol Hydrate
CAS:1837-57-6
MF:C18H21N3O4
MW:343.38
EINECS:217-408-1
Product Categories:Pharma;API's;1837-57-6
Mol File:1837-57-6.mol
6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Chemical Properties
Melting point 235°C
Boiling point 478.66°C (rough estimate)
density 1.2764 (rough estimate)
refractive index 1.5855 (estimate)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
CAS DataBase Reference1837-57-6(CAS DataBase Reference)
EPA Substance Registry SystemRivanol (1837-57-6)
Safety Information
MSDS Information
6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Usage And Synthesis
Chemical PropertiesPale-yellow crystals. Slowly soluble in 15 parts water; soluble in 9 parts boiling water; soluble in 110 parts alcohol (22C). Solutions are yellow, fluorescent, and stable to boiling.
OriginatorRivanol,Sopharma
Uses2-Ethoxy-6,9-diaminoacridine Lactate is used in treating purulent-necrotic wounds of hooves in cattle.
UsesBactericide, surgical antisepsis, preparation of pure γ-globulin.
Manufacturing ProcessA mixture of 250 parts by volume of ethylene glycol, 50 parts by weight of 6- nitro-9-chloro-2-ethoxyacridine (obtained by reaction of 52 parts by weight of 30 nitro-4-ethoxy-diphenylamine-6-carboxylic acid with phosphorous oxychloride), 10 parts by weight of ammonium chloride, and 11 parts by weight of urea were heated to 170°C and stirred for 1 hour at 170°-175°C. Subsequently, the whole was cooled to 100°C, the reaction mixture was introduced into 1000 parts by volume of water, rendered acidic to Congo paper by means of hydrochloric acid and the 6-nitro-9-amino-2-ethoxyacridine precipitated was filtered off. By reduction iron according to Bechamp, 6,9- diamino-2-ethoxy-acridine hydrochloride was obtained with yield of 83% as the yellow needles. The base was prepared by adding an equivalent of NaOH. MP: 124°C.In practice it is usually used as lactate.
Therapeutic FunctionAntiseptic, Antibacterial
Safety ProfilePoison by subcutaneous, intraperitoneal, and intravenous routes. Experimental reproductive effects. An antiseptic. When heated to decomposition it emits toxic fumes of NOx.
6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Preparation Products And Raw materials
Raw materialsEthylene glycol-->Phosphorus oxychloride

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