1-Hydroxy-2-naphthoic acid

1-Hydroxy-2-naphthoic acid
  • CAS No.:86-48-6
Other grades of this product :
1-Hydroxy-2-naphthoic acid Basic information
Product Name:1-Hydroxy-2-naphthoic acid
Synonyms:LABOTEST-BB LT00452757;RARECHEM AL BE 0359;Salmeterol Hydroxynaphthoic Acid Impurity (USP);ALPHA-HYDROXYNAPHTHOIC ACID;1-NAPHTHOL-2-CARBOXYLIC ACID;1-HYDROXY-2-NAPHTHOIC ACID;1-HYDROXY-NAPHTHALENE-2-CARBONIC ACID;1-Hydroxy-2-phthoic acid
CAS:86-48-6
MF:C11H8O3
MW:188.18
EINECS:201-674-0
Product Categories:Aromatics;Intermediates of Dyes and Pigments;bc0001
Mol File:86-48-6.mol
1-Hydroxy-2-naphthoic acid Chemical Properties
Melting point 195-200 °C (dec.) (lit.)
Boiling point 283.17°C (rough estimate)
density 1.2100 (rough estimate)
refractive index 1.6310 (estimate)
Fp 150 °C
storage temp. Sealed in dry,Room Temperature
solubility alcohol: freely soluble
form Powder or Crystals
pka3.02±0.30(Predicted)
color White to slightly pink to tan
Water Solubility SOLUBLE IN HOT WATER
Merck 14,4834
BRN 974438
InChIKeySJJCQDRGABAVBB-UHFFFAOYSA-N
CAS DataBase Reference86-48-6(CAS DataBase Reference)
EPA Substance Registry System1-Hydroxy-2-naphthoic acid (86-48-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39-37
WGK Germany 3
TSCA Yes
HS Code 29182910
MSDS Information
ProviderLanguage
1-Naphthol-2-carboxylic acid English
ACROS English
SigmaAldrich English
ALFA English
1-Hydroxy-2-naphthoic acid Usage And Synthesis
Chemical Propertiesbeige to brown-grey powder
UsesMetabolite from phenanthrene degradation.
UsesIt is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuff.
General Description1-Hydroxy-2-naphthoic acid is produced by the transformation of phenanthrene by NCIB 9816 clones.
Purification MethodsSuccessively crystallise the acid from EtOH/water, diethyl ether and acetonitrile, with filtration through a column of charcoal and Celite. [Tong & Glesmann J Am Chem Soc 79 583 1957, Beilstein 10 H 331, 10 IV 1194.]

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