Product

(R)-(+)-1-Boc-3-aminopyrrolidine

CAS No.：147081-49-0

Other grades of this product :

(R)-(+)-1-Boc-3-aminopyrrolidine Basic information

Product Name:	(R)-(+)-1-Boc-3-aminopyrrolidine
Synonyms:	1-Boc-3-(R )-aminopyrrolidine;(R)-3-Amino-1-Boc-pyrroli...;(3R)-3-Aminopyrrolidine, N1-BOC protected;1-PYRROLIDINECARBOXYLIC ACID, 3-AMINO-, 1,1-DIMETHYLETHYL ESTER, (3R);3-AMINO-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, (R);(R)-TERT-BUTYL 3-AMINOPYRROLIDINE-1-CARBOXYLATE;(R)-(+)-N-BOC-3-AMINOPYRROLIDINE;(R)-(+)-N-tert-Butoxycarbonyl-3-aminopyrroli
CAS:	147081-49-0
MF:	C9H18N2O2
MW:	186.25
EINECS:
Product Categories:	3-Aminopyrrolidines;Chiral 3-Aminopyrrolidines;pharmacetical;chiral;Pyrrole&Pyrrolidine&Pyrroline;Benzenes
Mol File:	147081-49-0.mol

(R)-(+)-1-Boc-3-aminopyrrolidine Chemical Properties

Melting point	243-244°C
Boiling point	243-244°C
density	1.098
refractive index	1.4720
Fp	196°F
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
form	Liquid
pka	9.55±0.20(Predicted)
color	Clear pale yellow
Sensitive	Air Sensitive
InChIKey	CMIBWIAICVBURI-SSDOTTSWSA-N
CAS DataBase Reference	147081-49-0(CAS DataBase Reference)

Safety Information

Hazard Codes	C,Xn
Risk Statements	22-41-44
Safety Statements	26-36/37/39
RIDADR	UN 2810 6.1/PG 3
WGK Germany	3
HazardClass	6.1
PackingGroup	Ⅲ
HS Code	29339900

MSDS Information

(R)-(+)-1-Boc-3-aminopyrrolidine Usage And Synthesis

Chemical Properties	Colorless to light yellow liqui
Uses	(R)-(+)-1-Boc-3-aminopyrrolidine may be used to prepare: Descarboxamide analog and N^a-methylated analogs of 4-N-(N^ω-nitro-L-argininyl)-trans-4-amino-L-proline amide. Histamine 3 (H₃) receptor antagonists containing pyrrolidin-3-yl-N-methylbenzamide moiety.

(R)-(+)-1-Boc-3-aminopyrrolidine Preparation Products And Raw materials

Raw materials

Ethanol-->Sodium hydroxide-->Methanol-->Tetrahydrofuran-->Dichloromethane-->Acetic acid-->Thionyl chloride-->Triethylamine-->Pyridine-->Palladium-->1,4-Dioxane-->Sodium borohydride-->Di-tert-butyl dicarbonate-->Calcium chloride-->Methanesulfonyl chloride-->Benzyl chloroformate-->Allylamine-->Benzyltrimethylammonium chloride-->D-Aspartic acid-->4-Nitrobenzyl chloroformate

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