1-Chloro-2-iodobenzene

1-Chloro-2-iodobenzene
  • CAS No.:615-41-8

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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1-Chloro-2-iodobenzene Basic information
Uses
Product Name:1-Chloro-2-iodobenzene
Synonyms:2-CHLORO-1-IODOBENZENE;2-CHLOROIODOBENZENE;1-chloro-2-iodo-benzen;2-Chlorophenyl iodide;2-Iodochlorobenzene;Benzene, 1-chloro-2-iodo-;O-IODOCHLOROBENZENE;O-CHLOROIODOBENZENE
CAS:615-41-8
MF:C6H4ClI
MW:238.45
EINECS:210-423-4
Product Categories:Chlorine Compounds;Iodine Compounds
Mol File:615-41-8.mol
1-Chloro-2-iodobenzene Chemical Properties
Melting point 1 °C (lit.)
Boiling point 234-235 °C (lit.)
density 1.952 g/mL at 25 °C (lit.)
refractive index n20/D 1.6334(lit.)
Fp 233 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility 0.069g/l
form Liquid
Specific Gravity1.952
color Clear slightly yellow
Water Solubility INSOLUBLE
Sensitive Light Sensitive
BRN 1905116
CAS DataBase Reference615-41-8(CAS DataBase Reference)
NIST Chemistry Reference1-Chloro-2-iodobenzene(615-41-8)
EPA Substance Registry SystemBenzene, 1-chloro-2-iodo- (615-41-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
RIDADR UN 2810
WGK Germany 3
F 8
TSCA T
HazardClass IRRITANT
HS Code 29036990
MSDS Information
ProviderLanguage
1-Chloro-2-iodobenzene English
SigmaAldrich English
ACROS English
ALFA English
1-Chloro-2-iodobenzene Usage And Synthesis
Useso-Iodochlorobenzene is a building block that has been used as a reactant for the synthesis of biaryl derivatives of seasamol used for their antioxidant activity against DPPH radical.
Chemical PropertiesClear colourless to light yellow liquid
Uses1-Chloro-2-iodobenzene is used as a precursor and involved in the preparation of 2,2'-dichloro-biphenyl. It is also used to prepare N,N-diaryl-o-phenylenediamines and 4(5)-(2-chlorophenyl)-1H-imidazole. It reacts with lanthanum metal in the presence of trimethylchlorosilane to prepare 1-chloro-2-trimethylsilylbenzene.
Uses1-Chloro-2-iodobenzene has been used in the preparation of N,N-diaryl-o-phenylenediamines and 4(5)-(2-chlorophenyl)-1H-imidazole.
General Description1-Chloro-2-iodobenzene reacts with lanthanum metal in the presence of trimethylchlorosilane to yield 1-chloro-2-trimethylsilylbenzene.

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