| Diethyl methylmalonate Basic information |
| Product Name: | Diethyl methylmalonate |
| Synonyms: | RARECHEM AL BI 0301;Diethyl methylmalonate 99%;METHYLMALONIC ACID DIETHYL ESTER;DIETHYL METHYLMALONATE;DIETHYL 2-METHYLPROPANEDIOATE;1,3-Diethyl 2-methylpropanedioate;Diethyl methylmalote;Methoxymalonic Acid Diethyl Ester |
| CAS: | 609-08-5 |
| MF: | C8H14O4 |
| MW: | 174.19 |
| EINECS: | 210-175-7 |
| Product Categories: | Building Blocks;C8 to C9;Carbonyl Compounds;Chemical Synthesis;Esters;Organic Building Blocks;Pharmaceutical Intermediates;Cyanoacetic acid esters;Hydrocyanic acid derivatives;bc0001 |
| Mol File: | 609-08-5.mol |
| Diethyl methylmalonate Chemical Properties |
| Boiling point | 198-199 °C (lit.) 78-80 °C/10 mmHg |
| density | 1.022 g/mL at 20 °C (lit.) |
| refractive index | n |
| Fp | 170 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 1000mg/l |
| form | Liquid |
| pka | 13.13±0.46(Predicted) |
| Specific Gravity | 1.013 |
| color | Clear colorless |
| PH | 8 (1000mg/l, H2O, 20℃) |
| Water Solubility | immiscible |
| BRN | 637028 |
| InChIKey | UPQZOUHVTJNGFK-UHFFFAOYSA-N |
| CAS DataBase Reference | 609-08-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Propanedioic acid, methyl-, diethyl ester(609-08-5) |
| EPA Substance Registry System | Propanedioic acid, methyl-, diethyl ester (609-08-5) |
| Safety Information |
| Safety Statements | 23-24/25 |
| WGK Germany | 3 |
| TSCA | Yes |
| HS Code | 29171990 |
| MSDS Information |
| Provider | Language |
|---|---|
| Diethyl methylmalonate | English |
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| Diethyl methylmalonate Usage And Synthesis |
| Chemical Properties | Clear liquid |
| Uses | Diethyl methylmalonate is used as intermediate for the syntheses of pharmaceuticals, e.g. non-steroidal anti-inflammatory agents with 2-acrylpropionic acid structures acrylpropionic acid structure. It is also used in the flavour and fragrance industries. Product Data Sheet |
| Uses | Diethyl methylmalonate was used to investigate the effect of direct supplementation of the medium with di-ester of methylmalonate on erythromycin fermentation in Saccharopolyspora erythraea mutB strain. |
| General Description | Diethyl methylmalonate reacts with 2-cyclohexenone under abnormal Michael conditions form 2-(3-oxocyclohexyl)-2-cyclohexenone. It causes the alkylation of poly(chloromethylstyrene) during pahse transfer catalysis. |
| Diethyl methylmalonate Preparation Products And Raw materials |
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