Product

6-(Chloromethyl)uracil

CAS No.：18592-13-7

Other grades of this product :

6-(Chloromethyl)uracil Basic information

Product Name:	6-(Chloromethyl)uracil
Synonyms:	6-Chloromethyl-1H-pyrimidine-2,4-dione;6-(Chloromethyl)uracil,98%;6-(chloroMethyl)-1,2,3,4-tetrahydropyriMidine-2,4-dione;2,4(1H,3H)-PyriMidinedione, 6-(chloroMethyl)-;Uracil, 6-(chloroMethyl)- (8CI);6-ChloroMethyluracil, 98.0%(T);3h)-pyrimidinedione,6-(chloromethyl)-4(1h;TIMTEC-BB SBB003961
CAS:	18592-13-7
MF:	C5H5ClN2O2
MW:	160.56
EINECS:	242-431-9
Product Categories:	Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks
Mol File:	18592-13-7.mol

6-(Chloromethyl)uracil Chemical Properties

Melting point	257 °C (dec.)(lit.)
density	1.393±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	almost transparency in N,N-DMF
form	powder to crystal
pka	7.91±0.10(Predicted)
color	White to Light yellow
InChIKey	VCFXBAPEXBTNEA-UHFFFAOYSA-N
CAS DataBase Reference	18592-13-7(CAS DataBase Reference)
EPA Substance Registry System	2,4(1H,3H)-Pyrimidinedione, 6-(chloromethyl)- (18592-13-7)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
Hazard Note	Irritant
TSCA	Yes
HS Code	29335990

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

6-(Chloromethyl)uracil Usage And Synthesis

Uses	6-(Chloromethyl)uracil is an alkali-resistant protein adsorbent, suitable for medical procedures. it is also used in the synthesis of chlorophenyl hydroxypiperidine analogs having anti-amylatic activity.

6-(Chloromethyl)uracil Preparation Products And Raw materials

Raw materials

2,4(1H,3H)-Pyrimidinedione, 6-(chloromethyl)-5-iodo--->6-[(methylthio)methyl]uracil-->6-(HYDROXYMETHYL)URACIL-->6-(CHLOROMETHYL)-2-(METHYLTHIO)PYRIMIDIN-4(3H)-ONE-->4-chloro-3-oxobutyryl chloride-->6-FORMYL-URACIL MONOHYDRATE-->6-Methyluracil-->Urea-->Pyridine-->Orotic acid-->Ethyl 4-chloroacetoacetate

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