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| 2'-Deoxyinosine Basic information |
| Product Name: | 2'-Deoxyinosine | | Synonyms: | Didanosine EP Impurity C;Didanosine Impurity Ⅲ:2'-Deoxyinosine;Didanosine Impurity 3（Didanosine EP Impurity C）;2'-Deoxyinosine(Di);DEOXYINOSINE, 2'-(RG);9-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-9H-purin-6-ol;9-((2R,4S,5R)-4-Hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol;1,9-Dihydro-9-(2'-deoxy-β-D-ribofuranosyl)-6H-purin-6-one | | CAS: | 890-38-0 | | MF: | C10H12N4O4 | | MW: | 252.23 | | EINECS: | 212-964-1 | | Product Categories: | Bases & Related Reagents;Heterocycles;Impurities;Inhibitors;Intermediates & Fine Chemicals;Nucleotides;Pharmaceutical Raw Materials;Pyridines, Pyrimidines, Purines and Pteredines;Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Pharmaceuticals;Heterocycles, Impurities, Inhibitors, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 890-38-0.mol |
| 2'-Deoxyinosine Chemical Properties |
| Melting point | 250 °C | | alpha | 21 º (c=1, H2O 22 ºC) | | Boiling point | 395.4°C (rough estimate) | | density | 1.3402 (rough estimate) | | refractive index | -16 ° (C=1, H2O) | | storage temp. | -20°C | | solubility | DMSO (Slightly), Water (Slightly) | | pka | 8.92±0.70(Predicted) | | form | Powder | | color | White to Off-white | | Water Solubility | 8.33g/L(25.02 ºC) | | BRN | 33517 | | CAS DataBase Reference | 890-38-0(CAS DataBase Reference) | | NIST Chemistry Reference | Inosine, 2'-deoxy-(890-38-0) |
| 2'-Deoxyinosine Usage And Synthesis |
| Chemical Properties | Crystalline | | Uses | An Inosine (I661000) analog with hypotensive activity. An impurity of the antiviral drug 2’,3’-Dideoxyinosine (D440950). | | Uses | 2′-Deoxyinosine has been used in the quantification of nucleoside forms of DNA lesion in a single DNA sample by liquid chromatography tandem mass spectrometry (LC-MS/MS). It has also been used as a standard for high performance liquid chromatography analysis. | | Biochem/physiol Actions | 2′-Deoxyinosine is a nucleoside form of hypoxanthine. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinosine is formed from nitrosative deamination by N2O3. | | Purification Methods | 2'-Deoxyinosine [890-38-0] M 252.2, m 206o(dec), 218-220o(dec), [ ] D25 -21o (c 2, N ] D -21o (c 1, H 2O), pKEst(1) ~ 8.9, pKEst(2) ~ 12.4. Purify 2'-deoxyinosine by recrystallisation from H2O. [Brown & Lythgoe J Chem Soc 1990 1950, UV: MacNutt Biochem J 50 384 1952, Beilstein 26 III/IV 2086.] |
| 2'-Deoxyinosine Preparation Products And Raw materials |
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