Other grades of this product :
| Vitamin K2(35) Basic information |
| Product Name: | Vitamin K2(35) | | Synonyms: | MENAQUINONE-7;(all-E)-2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione;Menaquinone K7;Vitamin K2(35);Vitamin MK 7;Menlaquinone 7;MK-7;2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptenyl]-3-methyl-1,4-naphthalenedione | | CAS: | 2124-57-4 | | MF: | C46H64O2 | | MW: | 649 | | EINECS: | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;APIs | | Mol File: | 2124-57-4.mol |
| Vitamin K2(35) Chemical Properties |
| Melting point | 54 °C | | Boiling point | bp0.0002 200° (some dec) | | density | 0.961 | | storage temp. | -20°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | form | Solid | | color | Pale Yellow to Yellow | | Stability: | Light and Temperature Sensitive | | InChI | InChI=1S/C46H64O2/c1-34(2)18-12-19-35(3)20-13-21-36(4)22-14-23-37(5)24-15-25-38(6)26-16-27-39(7)28-17-29-40(8)32-33-42-41(9)45(47)43-30-10-11-31-44(43)46(42)48/h10-11,18,20,22,24,26,28,30-32H,12-17,19,21,23,25,27,29,33H2,1-9H3/b35-20+,36-22+,37-24+,38-26+,39-28+,40-32+ | | InChIKey | RAKQPZMEYJZGPI-LJWNYQGCSA-N | | SMILES | C1(=O)C2=C(C=CC=C2)C(=O)C(C)=C1C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\C |
| Vitamin K2(35) Usage And Synthesis |
| Description | Menaquinone 7 (MK-7) is a vitamin K2 analog that has been found in a variety of fermented foods. It increases osteocalcin, osteoprotegerin, and RANKL mRNA expression in osteoblastic MC3T3E cells. MK-7 (1 μM) increases alkaline phosphatase activity and calcium content in femoral-metaphyseal tissues isolated from normal and skeletal-unloaded rats. In vivo, MK-7 (100 μg/g diet) inhibits aortic and myocardial calcification and decreases aortic alkaline phosphatase tissue concentrations in a rat model of extraosseous calcification. It also increases trabecular number, bone mineral density, and bone mineral content in a rat model of ovariectomy-induced bone loss. | | Chemical Properties | Light Yellow Crystalline Solid | | Uses | Vitamin (prothrombogenic) | | Uses | Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a vari
ety of physiological processes. Menaquinone 7 belongs to the class of K2-Vitamins homologs. Menaquinone 7 has been identified as the most bioactive cofactor for the carboxylation reaction of Gla-prote
ins such as osteocalcin and matrix-Gla protein, which plays a crucial role in building and maintaining overall bone health. | | Uses | Vitamin K2 (MK-7)-(5,6,7,8-d4,2-methyl-d3) can be used as a stable isotope internal standard for data interpretation in specific biological samples. | | Definition | ChEBI: A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation. | | General Description | Vitamin K2, also known as menaquinone, is a polyisoprenoid-substituted?napthoquinone. Menaquinone-7 (MK-7) is a subtype of vitamin K2. It is found in animals, soy protein, fermented products and is primarily produced by bacteria.Vitamin K2 (MK-7)-(5,6,7,8-d4,2-methyl-d3) is a deuterated vitamin K2 wherein C-5, C-6, C-7, C-8, and 2-methyl protons are replaced by deuterium. |
| Vitamin K2(35) Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye