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| (R)-1-Boc-3-Aminopiperidine Basic information |
| Product Name: | (R)-1-Boc-3-Aminopiperidine | | Synonyms: | tert-Butyl (3R)-3-aminopiperidine-1-carboxylate;(R)-3-Aminopiperidine, N1-BOC protected;(R)-1-t-Butyloxycarbonyl-3-aminopiperidine hydrochloride;(R)-1-Boc-3-piperidinamine, tert-Butyl (R)-3-amino-1-piperidinecarboxylate;(R)-3-Amino-1-N-Boc-Piperidine (R)-1-Boc-3-Aminopiperidine;1-TERT-BUTYLOXYCARBONYL-3-R-AMINOPIPERIDINE HYDROCHLORIDE;1-Piperidinecarboxylicacid,3-amino-,1,1-dimethylethylester,(3R)-(9CI);(R)-3-AMINO-N-BOC-PIPERIDINE | | CAS: | 188111-79-7 | | MF: | C10H20N2O2 | | MW: | 200.28 | | EINECS: | 628-472-9 | | Product Categories: | CHIRAL CHEMICALS;Piperidines;AMINOACID;pharmacetical;Piperidine;Piperidine Series | | Mol File: | 188111-79-7.mol |
| (R)-1-Boc-3-Aminopiperidine Chemical Properties |
| alpha | 28.5 º (c=1, DMF) | | Boiling point | 277.3±33.0 °C(Predicted) | | density | 1.041±0.06 g/cm3(Predicted) | | refractive index | 1.4730 | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | Chloroform (Slightly), DMF (Slightly), DMSO (Slightly) | | pka | 10.35±0.20(Predicted) | | form | Liquid | | color | Colorless to pale yellow | | optical activity | [α]/D -28.5±2°, c = 1 in DMF | | Water Solubility | Immiscible with water. | | Sensitive | Moisture Sensitive | | CAS DataBase Reference | 188111-79-7(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26 | | RIDADR | UN2735 | | WGK Germany | 3 | | F | 10-34 | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29333990 |
| (R)-1-Boc-3-Aminopiperidine Usage And Synthesis |
| Chemical Properties | Yellow liquid | | Uses | (R)-(-)-3-Amino-1-Boc-piperidine is used as an intermediate in the manufacture of various substances such as pharmaceuticals. | | Uses | (R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor. | | General Description | (R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents. |
| (R)-1-Boc-3-Aminopiperidine Preparation Products And Raw materials |
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