(S)-(+)-Mandelic acid

(S)-(+)-Mandelic acid
  • CAS No.:17199-29-0
Other grades of this product :
(S)-(+)-Mandelic acid Basic information
Product Name:(S)-(+)-Mandelic acid
Synonyms:(s)-(+)-mandelic;(s)-benzeneaceticaci;(S)-Hydroxyphenylaceticacid;Benzeneaceticacid,alpha-hydroxy-,(S)-;L-mandelate;(S)-(+)-MANDELIC ACID FOR RESOLUTION OF RACEMATES 99+%;L-(+)-Mandelic acid, 99+%;L-(+)-α-Hydroxybenzeneacetic acid
CAS:17199-29-0
MF:C8H8O3
MW:152.15
EINECS:241-240-8
Product Categories:Activators;Analytical Chemistry;Carboxylic Acids (Chiral);Chiral Building Blocks;e.e. / Absolute Configuration Determination (NMR);Enantiomer Excess & Absolute Configuration Determination;FINE Chemical & INTERMEDIATES;Chiral Compounds;Aromatic Phenylacetic Acids and Derivatives;chiral;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Chiral Compound;Cosmetic
Mol File:17199-29-0.mol
(S)-(+)-Mandelic acid Chemical Properties
Melting point 131-134 °C(lit.)
alpha 155 º (c=2 , H2O)
Boiling point 234.6°C (rough estimate)
density 1.3410
refractive index 153.5 ° (C=1, H2O)
Fp >190°C
storage temp. Store below +30°C.
solubility Methanol (Slightly), Water (Sparingly, Heated)
form Crystalline Powder
pka3.41±0.25(Predicted)
color White to beige-brown
PH2.1 (60g/l, H2O, 20℃)
optical activity[α]20/D +153±5°, c = 5% in H2O
Water Solubility 100 g/L (25 ºC)
Sensitive Light Sensitive
BRN 2208678
Stability:Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents, strong reducing agents.
CAS DataBase Reference17199-29-0(CAS DataBase Reference)
NIST Chemistry ReferenceBenzeneacetic acid, «alpha»-hydroxy-, (s)-(17199-29-0)
EPA Substance Registry SystemBenzeneacetic acid, .alpha.-hydroxy-, (.alpha.S)- (17199-29-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-37/39-26-36
WGK Germany 3
TSCA Yes
HS Code 29181980
MSDS Information
ProviderLanguage
D-2-Hydroxy-2-phenylacetic acid English
ACROS English
SigmaAldrich English
ALFA English
(S)-(+)-Mandelic acid Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powde
UsesAntiseptic (urinary).
Uses(S)-(+)-Mandelic acid is a versatile reagent used in the resolution of racemates and the preparation of amides, Pharmaceutical Intermediates.
UsesA versatile reagent used in the resolution of racemates and the preparation of amides.
Flammability and ExplosibilityNotclassified
Purification MethodsPurify the mandelic acids by recrystallisation from H2O, *C6H6 or CHCl3. [Roger J Chem Soc 2168 1932,Jamison & Turner J Chem Soc 611 1942.] They have solubilities in H2O of ca 11% at 25o. [Banks & Davies J Chem Soc 73 1938.] The S-benzylisothiuronium salts has m 180o (from H2O) and [] D 25 (+) and (-) 57o (c20, EtOH) [El Masri et al. Biochem J 68 199 1958]. [Beilstein 10 IV 564.]

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