Sodium taurocholate

CAS No.：145-42-6

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Sodium taurocholate Basic information

Product Name:	Sodium taurocholate
Synonyms:	2-([3-ALPHA,7-ALPHA,12-ALPHA-TRIHYDROXY-24-OXO-5-BETA-CHOLAN-24-YL]AMINO)ETHANESULFONIC ACID;ethanesulfonicacid,2-[[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24;monosodiumtaurocholicacid;n-choloyl-taurinsodiumsalt;taurocholatesodium;taurocholatesodiumsalt;5BETA-CHOLANIC ACID-3ALPHA,7ALPHA,12ALPHA-TRIOL 24-N-(2-SULFOETHYL) AMIDE SODIUM;5-BETA-CHOLANIC ACID-3-ALPHA, 7-ALPHA, 12-ALPHA-TRIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
CAS:	145-42-6
MF:	C26H44NNaO7S
MW:	537.68
EINECS:	205-653-7
Product Categories:	Bile Acids;Biochemistry;Steroids
Mol File:	145-42-6.mol

Sodium taurocholate Chemical Properties

Melting point	230 °C
alpha	23 º (c=3 H2O)
density	1.177 g/cm3(Temp: 22.5 °C)
refractive index	23 ° (C=3, H2O)
Fp	9℃
storage temp.	-20°C
solubility	H₂O: 0.5 M at 20 °C, clear, colorless to faintly yellow
form	neat
color	Brown to greenish brown
PH	pH (30g/l, 25℃) : 4.5～7.5
Water Solubility	> 250 g/L (20 ºC)
Decomposition	125°C
Merck	14,9075
BRN	3901620
CAS DataBase Reference	145-42-6(CAS DataBase Reference)
EPA Substance Registry System	Ethanesulfonic acid, 2-[[(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt (145-42-6)

Safety Information

Risk Statements	36/37/38
Safety Statements	26-36/37/39-24/25
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	3
RTECS	WX0400000
F	3-10
HS Code	29049090

MSDS Information

Provider	Language
Sodium 2-[(3a,7a,12a-trihydroxy-24-oxo-5beta-cholan-24-yl)amino]ethanesulfonate	English

Sodium taurocholate Usage And Synthesis

Chemical Properties	White to off-white powder
Uses	selectively activates retinoid X receptors (RXRs)
Uses	Sodium taurocholate is a detergent useful for the solubilization of lipids and membrane-bound proteins.
Purification Methods	Purify it by recrystallisation and gel chromatography using Sephadex LH-20. [Beilstein 10 III 1655, 10 IV 2078.]

Sodium taurocholate Preparation Products And Raw materials

Raw materials

Cholic acid

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