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| 2-Amino-2-methyl-1,3-propanediol Basic information |
| 2-Amino-2-methyl-1,3-propanediol Chemical Properties |
| Melting point | 100-110 °C (lit.) | | Boiling point | 151 °C/10 mmHg (lit.) | | density | 1.0509 (estimate) | | vapor density | 3.63 (vs air) | | vapor pressure | ~10 mm Hg ( 152 °C) | | refractive index | 1.4754 (estimate) | | Fp | >100°C | | storage temp. | Store below +30°C. | | solubility | H2O: 1 M at 20 °C, clear, colorless | | form | Crystalline Powder | | color | White | | PH | 10.0-12.0 (20℃, 0.5M in H2O) | | pka | 8.8(at 25℃) | | PH Range | 7.8 - 9.7 | | Water Solubility | 2500 g/L (20 ºC) | | λmax | λ: 260 nm Amax: 0.05λ: 280 nm Amax: 0.03 | | Merck | 13,447 | | BRN | 635708 | | Stability: | Stable. Combustible. May be moisture-sensitive. Incompatible with strong oxidizing agents, copper, aluminium, brass, strong acids. | | LogP | -1.31 at 22℃ | | CAS DataBase Reference | 115-69-5(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Amino-2-methyl-1,3-propanediol(115-69-5) | | EPA Substance Registry System | 1,3-Propanediol, 2-amino-2-methyl- (115-69-5) |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-20/21/22 | | Safety Statements | 26-36-37/39 | | RIDADR | UN 3259 8/PG 2 | | WGK Germany | 1 | | RTECS | TY2975000 | | F | 3-23 | | TSCA | Yes | | PackingGroup | III | | HS Code | 29221980 | | Toxicity | LD50 orally in Rabbit: 17000 mg/kg |
| 2-Amino-2-methyl-1,3-propanediol Usage And Synthesis |
| Chemical Properties | white powder | | Uses | Emulsifying agent (in soap form) for oils, fats, and waxes; absorbent for acidic gases; organic synthesis; cosmetics. | | Uses | A useful biological buffer2-Amino-2-methyl-1,3-propanediol is used to make surfactants, vulcanization accelerators and as a biological buffer. It acts as an absorbent for acidic gases and emulsifying agent for cosmetics, mineral oil, leather dressings, textile specialties and cleaning compounds. It is also used in hair sprays. It acts as a buffer for the determination of alkaline phosphatase activity and spacer in isotachophoresis of proteins. It serves as a reaction buffer for enzymes with an activity in the basic pH range such as alkaline phosphatase. Further, it is used in the preparation of 4-hydroxymethyl-4-methyl-oxazolidin-2-one. | | Definition | ChEBI: An aminodiol that is propane-1,3-diol substituted ny an amino and a methyl group at position 2. | | Purification Methods | Crystallise the diol three times from MeOH, dry in a stream of dry N2 at room temperature, then in a vacuum oven at 55o. Store it over CaCl2 [Hetzer & Bates J Phys Chem 66 308 1962]. [Beilstein 4 IV 1881.] |
| 2-Amino-2-methyl-1,3-propanediol Preparation Products And Raw materials |
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