BOC-8-AMINOCAPRYLIC ACID

BOC-8-AMINOCAPRYLIC ACID
  • CAS No.:30100-16-4

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
BOC-8-AMINOCAPRYLIC ACID Basic information
Product Name:BOC-8-AMINOCAPRYLIC ACID
Synonyms:RARECHEM EM WB 0025;T-BUTOXYCARBONYL-8-AMINOCAPRYLIC ACID;T-BUTOXYCARBONYL-8-AMINOOCTANOIC ACID;N-TERT-BUTYLOXYCARBONYL-8-AMINO-OCTANOIC ACID;8-(BOC-AMINO)CAPRYLIC ACID;8-(BOC-AMINO)OCTANOIC ACID;BOC-NH-(CH2)7-COOH;BOC-AMINOCAPRYLIC ACID
CAS:30100-16-4
MF:C13H25NO4
MW:259.34
EINECS:
Product Categories:Amino Acids
Mol File:30100-16-4.mol
BOC-8-AMINOCAPRYLIC ACID Chemical Properties
Melting point 56-59 °C
Boiling point 406.0±28.0 °C(Predicted)
density 1.036±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka4.78±0.10(Predicted)
BRN 2268966
Safety Information
WGK Germany 3
HazardClass IRRITANT
HS Code 29241990
MSDS Information
ProviderLanguage
SigmaAldrich English
BOC-8-AMINOCAPRYLIC ACID Usage And Synthesis
DescriptionBoc-8-aoc-oh can be used as a PROTAC linker in the synthesis of PROTACs. Boc-8-aoc-oh is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Chemical PropertiesWhite amorphous powder
UsesReagent to introduce a protected w-amino alkyl spacer. Longer spacer arms often impart increased activity to the substrate
BOC-8-AMINOCAPRYLIC ACID Preparation Products And Raw materials

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