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| Nicotinamide-N-oxide Basic information |
| Nicotinamide-N-oxide Chemical Properties |
| Melting point | 291-293 °C (dec.)(lit.) | | Boiling point | 253.51°C (rough estimate) | | density | 1.3471 (rough estimate) | | refractive index | 1.5100 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) | | form | Solid | | pka | 14.38±0.50(Predicted) | | color | White to Off-White | | Sensitive | Hygroscopic | | CAS DataBase Reference | 1986-81-8(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 29339900 |
| Nicotinamide-N-oxide Usage And Synthesis |
| Description | Nicotinamide N-oxide is a metabolite of nicotinamide . It is formed via oxidation of nicotinamide by the cytochrome P450 (CYP) isoform CYP2E1. Nicotinamide N-oxide (30 mM) inhibits proliferation and induces reduction of nitroblue tetrazolium (NBT; ), indicating cell differentiation, in HL-60 promyelocytic leukemia cells. Urine levels of nicotinamide N-oxide are elevated in a mouse model of high-fat diet-induced obesity. | | Chemical Properties | WHITE TO SLIGHTLY YELLOW FLUFFY CRYST. NEEDLES | | Uses | A metabolite of Nicotinamide | | Uses | A metabolite of Nicotinamide. |
| Nicotinamide-N-oxide Preparation Products And Raw materials |
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