(±)-Cloprostenol sodium salt

(±)-Cloprostenol sodium salt
  • CAS No.:55028-72-3
Other grades of this product :
(±)-Cloprostenol sodium salt Basic information
Product Name:(±)-Cloprostenol sodium salt
Synonyms:15-EPI CLOPROSTENOL;15(S)-CLOPROSTENOL;16-(3-CHLOROPHENOXY)-9,11,15R-TRIHYDROXY-17,18,19,20-TETRANORPROSTA-5Z,13E-DIEN-1-OIC ACID SODIUM SALT;(+)-16-M-CHLOROPHENOXY TETRANOR PROSTAGLANDIN F2ALPHA SODIUM SALT;7-(2-[4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3,5-dihydroxycyclopentyl)-5-heptenoic acid;(5Z)-rel-Cloprostenol SodiuM;DL-Cloprostenol sodiuM;(+/-)-16-(3-Chlorophenoxy)-9,11,15R-trihydroxy-17,18,19,20-tetranorprosta-5Z,13E-dien-1-oic acid hydrate sodium salt
CAS:55028-72-3
MF:C22H30ClNaO6
MW:448.92
EINECS:259-439-3
Product Categories:Other APIs;Pharmaceuticals;Pharmaceutical Raw Materials;Prostaglandins;Chiral Reagents;Intermediates & Fine Chemicals
Mol File:55028-72-3.mol
(±)-Cloprostenol sodium salt Chemical Properties
Melting point 68-70 °C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility H2O: >10 mg/mL
form solid
color light brown
InChIKeyIFEJLMHZNQJGQU-KXXGZHCCSA-M
CAS DataBase Reference55028-72-3(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 60-22-36/37/38
Safety Statements 53-26-36/37/39-45
WGK Germany 3
HS Code 2937500000
MSDS Information
(±)-Cloprostenol sodium salt Usage And Synthesis
Description±)-Cloprostenol sodium salt is the d-enantiomer of Cloprostenol (C587300), an aryl-oxymethyl analog of prostaglandin F2α.
Uses(±)-Cloprostenol sodium salt is a prostaglandin that dissolves the corpus luteum of cattle and is used as a veterinary drug.
Brand nameEstrumate(Bayer Animal Health).
General DescriptionCloprostenol sodium (Estrumate)is available as the sodium salt from Bayer AgriculturalDivision or Bayvet Division of Miles Laboratory as an aqueoussolution containing 250 mg/mL.
Biological ActivityWater-soluble prostaglandin F 2 α (PGF 2 α ) analog; acts as a potent FP receptor agonist (EC 50 = 0.84 nM). Potently inhibits differentiation of adipocyte precursor cells. Luteolytic agent in vivo .
Veterinary Drugs and TreatmentsCloprostenol is approved for use in beef or dairy cattle to induce luteolysis. It is recommended by the manufacturer for unobserved or undetected estrus in cows cycling normally, pyometra or chronic endometritis, expulsion of mummified fetus, luteal cysts, induced abortions after mismating, and to schedule estrus and ovulation for controlled breeding. Cloprostenol has been used in dogs for pregnancy termination and treatment of open pyometra. The use of cloprostenol for pyometra is controversial as some believe dinoprost (PGF2alpha) is more effective and has fewer adverse effects than cloprostenol.
Solubility in waterSoluble in H2O.
(±)-Cloprostenol sodium salt Preparation Products And Raw materials

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