Product

(S)-(-)-1-tert-Butoxycarbonyl-3-aminopyrrolidine

CAS No.：147081-44-5

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(S)-(-)-1-tert-Butoxycarbonyl-3-aminopyrrolidine Basic information

Product Name:	(S)-(-)-1-tert-Butoxycarbonyl-3-aminopyrrolidine
Synonyms:	(s)-n-boc-3-aminopyrrolidine;tert-Butyl (3S)-3-aminopyrrolidine-1-carboxylate;tert-Butyl (3S)-3-aminopyrrolidine-1-carboxylate, (3S)-3-Amino-1-(tert-butoxycarbonyl)pyrolidine;1-t-butoxycarbonyl-3-S-aMinopyrrolidine;(3S)-(-)-1-Boc-3-aminopyrrolidine (3S)-(-)-3-Amino-1-(tert-butoxycarbonyl)pyrrolidine (3S)-(-)-3-Amino-1-Boc-pyrrolidine;(S)-3-Amino-n-boc-pyrr;(S)-3-Amino-1-Boc-pyrroli...;(3S)-3-Aminopyrrolidine, N1-BOC protected
CAS:	147081-44-5
MF:	C9H18N2O2
MW:	186.25
EINECS:	627-302-0
Product Categories:	Chiral Building Blocks;Heterocyclic Building Blocks;Benzenes;3-Aminopyrrolidines;Chiral 3-Aminopyrrolidines;Pyrrolidines;pharmacetical;chiral;Pyrrole&Pyrrolidine&Pyrroline
Mol File:	147081-44-5.mol

(S)-(-)-1-tert-Butoxycarbonyl-3-aminopyrrolidine Chemical Properties

alpha	-2 º (c=1, chloroform)
Boiling point	216-217 °C(lit.)
density	1.067 g/mL at 25 °C(lit.)
refractive index	n20/D 1.4720(lit.)
Fp	196 °F
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
form	Liquid
pka	9.55±0.20(Predicted)
color	Clear colorless to yellow
optical activity	[α]20/D 2°, c = 1 in chloroform
Sensitive	Air Sensitive
BRN	8312125
CAS DataBase Reference	147081-44-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn,C,Xi
Risk Statements	22-41
Safety Statements	26
RIDADR	UN 2810 6.1/PG 3
WGK Germany	2
HazardClass	8
PackingGroup	III
HS Code	29339900

MSDS Information

Provider	Language
(S)-(-)-1-tert-Butoxycarbonyl-3-aminopyrrolidine	English
SigmaAldrich	English
ALFA	English

(S)-(-)-1-tert-Butoxycarbonyl-3-aminopyrrolidine Usage And Synthesis

Chemical Properties	Colorless to light yellow liqui
Uses	(S)-(-)-1-Boc-3-aminopyrrolidine may be used to prepare: Descarboxamide analog of 4-N-(N^ω-nitro-L-argininyl)-trans-4-amino-L-proline amide. Histamine 3 (H₃) receptor antagonists containing pyrrolidin-3-yl-N-methylbenzamide moiety.

(S)-(-)-1-tert-Butoxycarbonyl-3-aminopyrrolidine Preparation Products And Raw materials

Raw materials	Sodium hydroxide-->Ammonium hydroxide-->Isopropyl alcohol-->Di-tert-butyl dicarbonate-->1-Butanol-->(3S)-(+)-3-Aminopyrrolidine dihydrochloride-->tert-Butyl (3S)-3-(trifluoroacetamido)pyrrolidine-1-carboxylate-->(R)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester-->(3S)-1-Boc-3-azido-pyrrolidine-->ethyl 2-chloro-4-ethoxy-nicotinate
Preparation Products	Leniolisib

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