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| Isochlorogenic acid A Basic information |
| Product Name: | Isochlorogenic acid A | | Synonyms: | 3,5-Dicaffeoylquinic acid;Isochlorogenic acid A;Isochlorogenic acid A，3,5-Dicaffeoylquinic acid;3α,5β-Bis[[1-oxo-3-(3,4-dihydroxyphenyl)-2-propenyl]oxy]-1α,4α-dihydroxycyclohexane-1-carboxylic acid;1α,4α-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)propenoyloxy]cyclohexanecarboxylic acid;1β,4β-Dihydroxy-3β,5α-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1α-cyclohexanecarboxylic acid;1β,4β-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)acryloyloxy]cyclohexane-1-carboxylic acid;1β,4β-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)propenoyloxy]cyclohexanecarboxylic acid | | CAS: | 2450-53-5 | | MF: | C25H24O12 | | MW: | 516.46 | | EINECS: | | Product Categories: | The group of Chlorogenic acid;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Aromatic Phenols | | Mol File: | 2450-53-5.mol |
| Isochlorogenic acid A Chemical Properties |
| Melting point | >175°C (dec.) | | Boiling point | 826.2±65.0 °C(Predicted) | | density | 1?+-.0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Off-white to yellow/brown crystalline solid. | | pka | 3.54±0.50(Predicted) | | color | Off-White to Pale Yellow | | Stability: | Hygroscopic | | InChIKey | KRZBCHWVBQOTNZ-PSEXTPKNSA-N |
| Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | GU8403966 | | HS Code | 29189900 |
| Isochlorogenic acid A Usage And Synthesis |
| Description | 3,5-Dicaffeoylquinic acid (3,5-DCQA) is a natural phenolic compound that has been found in L. japonica, I. kaushue, and other plants. It has antioxidant, anti-inflammatory, and antiviral biological activities. 3,5-DCQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay (IC50 = 71.8 μM) and inhibits superoxide production in human neutrophils activated by N-formyl-Met-Leu-Phe (fMLF) and cytochalasin B (IC50 = 1.92 μM). It inhibits HIV-1 integrase 3''-end processing, strand transfer, and disintegration in a cell-free assay (IC50s = 0.33, 0.34, and 0.66 μg/ml, respectively) and inhibits HIV-1-induced cytotoxicity in MT-2 cells (ED50 = 1 μg/ml). In vivo, 3,5-DCQA (25 mg/kg) protects mice from acute lung injury induced by LPS and decreases neutrophil count in bronchoalveolar lavage fluid (BALF). | | Uses | Isochlorogenic Acid A is a phenolic compound shown to provide protection against oxidative stress cells. DNA protective agent. |
| Isochlorogenic acid A Preparation Products And Raw materials |
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