10-Hydroxy-2-decenoic acid

10-Hydroxy-2-decenoic acid
  • CAS No.:14113-05-4

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
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10-Hydroxy-2-decenoic acid Basic information
Product Name:10-Hydroxy-2-decenoic acid
Synonyms:HYDROXY-2-DECENOIC ACID, (E)-10-(10-HDA)(P);hydroxy-decenouc acid;jelly acid;trans-10-Hydroxy-2-decenoic Acid;(E)-10-hydroxydec-2-enoic acid;Queen been acid;10-HAD,10-hydroxydec-2-enoic acid;OMEGA-HYDROXY C10:1 (2-TRANS)
CAS:14113-05-4
MF:C10H18O3
MW:186.25
EINECS:808-119-7
Product Categories:1
Mol File:14113-05-4.mol
10-Hydroxy-2-decenoic acid Chemical Properties
Melting point 64.0 to 68.0 °C
Boiling point 339.2±15.0 °C(Predicted)
density 1.038±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder to crystal
pka4.78±0.10(Predicted)
color White to Almost white
CAS DataBase Reference14113-05-4(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
HS Code 29181990
MSDS Information
10-Hydroxy-2-decenoic acid Usage And Synthesis
Description10-HDA is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees. 10-HDA has longevity-promoting effects in C. elegans at a concentration of 25 μM. It down-regulates matrix metalloproteinases (MMPs) in rheumatoid arthritis synovial fibroblasts at a concentration of 1.25 nM and inhibits VEGF-induced angiogenesis in HUVECs at 500 μM. 10-HDA also facilitates differentiation of neurons from neural stem/progenitor cells and promotes collagen production by skin fibroblasts at concentrations of 100 μM and 1.5 mM, respectively.
DefinitionChEBI: An omega-hydroxy amino acid that is 2-decenoic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group and in which the C=C double bond has E configuration. It is a component of ro al jelly.
10-Hydroxy-2-decenoic acid Preparation Products And Raw materials

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