Other grades of this product :
| Ecdysone Basic information |
| Product Name: | Ecdysone | | Synonyms: | 2,3,14,22,25-pentahydroxy-,(2-beta,3-beta,5-beta,22r)-cholest-7-en-6-on;2-beta,3-beta,14,22,25-pentahydroxy-,(20s,22r)-5-beta-cholest-7-en-6-on;ECDYSONE;ECDYSONE, ALPHA-;ALPHA-ECDYSON;ALPHA-ECDYSONE;ALPHA-ECDYSTERONE;7,(5-ALPHA)-CHOLESTEN-2-BETA, 3-BETA, 14-ALPHA, 22R, 25-PENTOL-6-ONE | | CAS: | 3604-87-3 | | MF: | C27H44O6 | | MW: | 464.63 | | EINECS: | 222-760-4 | | Product Categories: | Natural Plant Extract;Steroids | | Mol File: | 3604-87-3.mol |
| Ecdysone Chemical Properties |
| Melting point | 242°C | | alpha | 20578 +62° | | Boiling point | 488.1°C (rough estimate) | | density | 1.0493 (rough estimate) | | refractive index | 1.4482 (estimate) | | storage temp. | 2-8°C | | solubility | Methanol (Very Slightly, Heated) | | form | Solid | | pka | 14.07±0.70(Predicted) | | color | White to Off-White | | Merck | 13,3525 | | BRN | 2422986 | | CAS DataBase Reference | 3604-87-3(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | FZ8170000 | | F | 10 |
| Ecdysone Usage And Synthesis |
| Uses | α-Ecdysone is a steroidal prohormone. | | Metabolic pathway | When white mice are administered 3H-ecdyson,
(2b,3b,14a,22(R),25-pentahydroxy-5b-cholest-7-ene-6-
one) by injection intraperitoneally, ecdysone is
metabolized via hydroxylation at C14, followed by
reduction of ring B into the 6a-hydroxy derivative and
epimerization at C3. | | Purification Methods | Recrystallise -ecdyson from tetrahydrofuran/pet ether and from H2O as a hydrate. It has been purified by chromatogaphy on Al2O3 and elution with EtOAc/MeOH. It has max at 242nm ( 12,400). Its acetate has m 214-216o from EtOAc/pet ether, and the 2,4-dinitrophenylhydrazone has m 170-175o(dec) from EtOAc. [Karlson & Hoffmeister Justus Liebigs Ann Chem 662 1 1963, Karlson Pure Appl Chem 14 75 1967, Beilstein 8 IV 3613.] |
| Ecdysone Preparation Products And Raw materials |
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