Etonogestrel

Etonogestrel
  • CAS No.:54048-10-1
Other grades of this product :
Etonogestrel Basic information
Product Name:Etonogestrel
Synonyms:Desogestrel Related CoMpound C;13-ethyl-17-ethynyl-17-hydroxy-11-methylidene-2,6,7,8,9,10,12,13,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-one;3-KETO DESOGESTREL;ETONOGESTREL;(17alpha)-13-ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one;3-Ketodesogestrel,3-Oxodesogestrel,Org-3236,Implanon;(17R)-13-Ethyl-17-hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one;Desogestrel Related Compound C (25 mg) (3-Keto-desogestrel)
CAS:54048-10-1
MF:C22H28O2
MW:324.46
EINECS:258-936-2
Product Categories:API;Inhibitors;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Hormone Drugs;Pharmaceuticals;Steroids
Mol File:54048-10-1.mol
Etonogestrel Chemical Properties
Melting point 182-184°C
Boiling point 473.1±45.0 °C(Predicted)
alpha D +87.6°
density 1.13±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: >5mg/mL
pka13.04±0.40(Predicted)
form powder
color white to beige
optical activity[α]/D +80 to +95°, c = 1 (CHCl3)
InChIKeyGCKFUYQCUCGESZ-BPIQYHPVSA-N
CAS DataBase Reference54048-10-1(CAS DataBase Reference)
Safety Information
Risk Statements 60-40
WGK Germany 3
RTECS JF8290000
HS Code 2937230000
MSDS Information
Etonogestrel Usage And Synthesis
Chemical PropertiesWhite Solid
UsesA biologically active metabolite of Desogestrel.
Brand nameImplanon (Organon).
General DescriptionEtonogestrel, 17α-13-ethyl-17hydroxy-11-methylene-18,19-dinorpregn-4-en-20-yn-3-one,3-ketodesogestrel, is the active metabolite of desogestrel. It isthe progestin component in a newer implantable contraceptive(Implanon) and in the vaginal contraceptive ring (NuvaRing).
Biochem/physiol ActionsEtonogestrel is a lipophilic molecule. Pharmacokinetics studies reveal that etonogestrel is bound to protein albumin in the blood. This remains independent of both endogenous and exogenous concentration of estradiol.
Etonogestrel Preparation Products And Raw materials

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