6-Bromo-1,3-dihydro-2H-indol-2-one

6-Bromo-1,3-dihydro-2H-indol-2-one
  • CAS No.:99365-40-9
Other grades of this product :
6-Bromo-1,3-dihydro-2H-indol-2-one Basic information
Product Name:6-Bromo-1,3-dihydro-2H-indol-2-one
Synonyms:6-BROMO-1,3-DIHYDRO-INDOL-2-ONE;6-BROMO-2-OXYINDOLE;6-BROMO-2-OXINDOLE;6-BROMOOXINDOLE;BROMOOXINDOLE (6-);6-Bromo-1,3-dihydro-2H-indol-2-one;6-Bromooxoindole;6-Bromoxoindole
CAS:99365-40-9
MF:C8H6BrNO
MW:212.04
EINECS:800-899-7
Product Categories:Heterocycle-Indole series;Aromatics;Indoline & Oxindole;Heterocycles;Indole Derivatives;Intermediates;blocks;Bromides;IndolesOxindoles;Halogenated Heterocycles;Heterocyclic Building Blocks;Indoles;IndolesBuilding Blocks
Mol File:99365-40-9.mol
6-Bromo-1,3-dihydro-2H-indol-2-one Chemical Properties
Melting point 217-221 °C(lit.)
Boiling point 343.6±42.0 °C(Predicted)
density 1.666±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSo
form Solid
pka13.39±0.20(Predicted)
color Orange
Water Solubility Slightly soluble in water.
InChIKeyJARRYVQFBQVOBE-UHFFFAOYSA-N
CAS DataBase Reference99365-40-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39-24/25
WGK Germany 3
Hazard Note Irritant
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
6-Bromo-1,3-dihydro-2H-indol-2-one Usage And Synthesis
Chemical PropertiesLight yelllow crystal
Uses6-Bromo-2-Oxindole is an indolinone derivative used for the preparation of p38α inhibitors as potential antiinflammatories.
Uses6-Bromooxindole derivative is used in the preparation of p38alpha inhibitors as potential anti- inflammatories. It is used as an intermediate in pharmaceuticals.
6-Bromo-1,3-dihydro-2H-indol-2-one Preparation Products And Raw materials
Preparation Products6'-Bromo-1'H-spiro[cyclopropane-1,3'-indole]-2'-one-->6-Bromo-1-methylindolin-2-one-->6-Bromoisatin

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