D(+)-Ribonic acid gamma-lactone

CAS No.：5336-08-3

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D(+)-Ribonic acid gamma-lactone Basic information

Product Name:	D(+)-Ribonic acid gamma-lactone
Synonyms:	D-RIBOSE-LACTONE;D-(+)-RIBONIC ACID GAMMA-LACTON;D(+)-RIBONIC ACID GAMMA-LACTONE;D-(+)-RIBONIC ACID G-LACTONE;D-(+)-RIBONIC GAMMA-LACTONE;D(+)-RIBONO-1,4-LACTONE;D-RIBONO-1,4-LACTONE;D-(+)-RIBONO-GAMMA-LACTONE
CAS:	5336-08-3
MF:	C5H8O5
MW:	148.11
EINECS:	226-256-5
Product Categories:	Inhibitors;13C & 2H Sugars;Biochemistry;Ribose;Sugar Acids;Sugars;Sugars, Carbohydrates & Glucosides;Dextrins、Sugar & Carbohydrates;Carbohydrates & Derivatives
Mol File:	5336-08-3.mol

D(+)-Ribonic acid gamma-lactone Chemical Properties

Melting point	85-87 °C(lit.)
alpha	18 º (c=5, H2O)
Boiling point	188.68°C (rough estimate)
density	1.2336 (rough estimate)
refractive index	18 ° (C=1, H2O)
storage temp.	Sealed in dry,Room Temperature
solubility	H₂O: 0.1 g/mL, clear
form	Powder
pka	12.10±0.60(Predicted)
color	White to Pale Yellow
optical activity	[α]24/D +18°, c = 1 in H2O
Water Solubility	soluble
BRN	82057
Stability:	Stable
CAS DataBase Reference	5336-08-3(CAS DataBase Reference)
NIST Chemistry Reference	D-(+)-Ribonic acid gamma-lactone(5336-08-3)

Safety Information

Safety Statements	22-24/25
WGK Germany	3
HS Code	29322090

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

D(+)-Ribonic acid gamma-lactone Usage And Synthesis

Chemical Properties	White Crystalline Solid
Uses	A sugar lactone as inhibitor of β-galactosidase of E. coli.
Uses	Important chiral synthon
Uses	D-ribono-1,4-lactone is a compound useful in organic synthesis.
Definition	ChEBI: A five-membered form of ribonolactone having D-configuration.
Purification Methods	Purify D-(+)-ribonic acid--lactone by recrystallisation from EtOAc. The tribenzoate has m 54-56o (from AcOH), [] D 25 +27o (c 2.37, Me2NCHO), and the 3,5-O-benzylidene derivative has m 230-231.5o (needles from Me2CO-pet ether) and [] D 25 -177o (CHCl3). [Chen & Joulié J Org Chem 49 2168 1984, Zinner & Voigt J Carbohydr Research 7 38 1968.]

D(+)-Ribonic acid gamma-lactone Preparation Products And Raw materials

Raw materials	RIBONIC ACID
Preparation Products	1-deoxy-1-(6-phenylazo-3,4-xylidino)-D-ribitol-->2,3-O-Isopropylidene-D-lyxono-1,4-lactone-->(S)-5-Hydroxymethyldihydrofuran-2-one

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