1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE

CAS No.：306-37-6

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This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE Basic information

Product Name:	1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE
Synonyms:	1,2-DimethylhydrazinediHCl;sym-Dimethylhydrazine dihydrochloride, 99+%;Hydrazine, 1,2-dimethyl-, dihydrochloride;1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE (SYM-, N,N''-) 98+%;1,2-Dimethylhydrazine dihydrochloride, N,Nμ-Dimethylhydrazine (sym.) dihydrochloride;N,Nzzhlxy-Dimethylhydrazine dihydrochloride (sym.);syM-DiMethylhydrazine dihydrochloride, 99+% 10GR;N,N'-DiMethylhydrazine dihydrochloride 98%
CAS:	306-37-6
MF:	C2H10Cl2N2
MW:	133.02
EINECS:	206-183-5
Product Categories:
Mol File:	306-37-6.mol

1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE Chemical Properties

Melting point	167-169 °C (dec.)(lit.)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	Crystalline Flakes or Powder
color	White to light yellow
Water Solubility	almost transparency
Merck	14,3248
BRN	3905684
CAS DataBase Reference	306-37-6(CAS DataBase Reference)
EPA Substance Registry System	1,2-Dimethylhydrazine dihydrochloride (306-37-6)

Safety Information

Hazard Codes	T,N
Risk Statements	45-23/24/25-51/53
Safety Statements	53-45-61
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	MV2800000
HazardClass	6.1(b)
PackingGroup	III
HS Code	29280090

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE Usage And Synthesis

Chemical Properties	white to light yellow crystalline flakes
Uses	carcinogen
Uses	1,2-Dimethylhydrazine is a potent carcinogen that acts as a DNA alkylating agent. It is used to induce colon tumors in experimental animals. It was also used in preparation of spiroisoquinolinedione aldose reductase inhibitors.
Definition	ChEBI: A hydrochloride resulting from the reaction of 1,2,dimethylhydrazine with 2 mol eq. of hydrogen chloride.
General Description	Prisms (from water) or white crystalline powder. Distinct amine fishy or ammonia-like odor.
Air & Water Reactions	Extremely hygroscopic. Water soluble.
Reactivity Profile	1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE is a reducing agent. Incompatible with oxidizing agents and bases.
Fire Hazard	Flash point data for 1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE are not available; however, 1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE is probably combustible.
Biochem/physiol Actions	Induces colon cancer in rats and mice.
Safety Profile	Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion and subcutaneous routes. Experimental reproductive effects. Mutation data reported. A rocket fuel. When heated to decomposition it emits very toxic fumes of HCl and NOx

1,2-DIMETHYLHYDRAZINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Ethanol-->Hydrochloric acid-->Tetrahydrofuran-->Acetic acid-->Sodium hydride-->Dimethyl sulfate-->Iodomethane-->Hydrazinium hydroxide solution-->Tosyl chloride-->Benzoyl chloride-->Hydrazine sulfate-->1,1-Dimethylhydrazine-->N,N'-DIBENZOYLHYDRAZINE

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