6-Aminoindole

6-Aminoindole
  • CAS No.:5318-27-4
Other grades of this product :
6-Aminoindole Basic information
Product Name:6-Aminoindole
Synonyms:INDOLE-6-AMINE;1H-INDOL-6-AMINE;6-AMINOINDOLE;6-AMINO-1H-INDOLE;6-Indolamine;6-AMinoindole, 97+%;2,3-Dihydro-1H-indol-6-amine;6-Aminoindole ,98%
CAS:5318-27-4
MF:C8H8N2
MW:132.16
EINECS:627-713-5
Product Categories:Simple Indoles;Building Blocks;Indoles and derivatives;Indole;Indoles;Heterocyclic Building Blocks;Heterocycle-Indole series
Mol File:5318-27-4.mol
6-Aminoindole Chemical Properties
Melting point 75-79 °C
Boiling point 161-166°C 2mm
density 1.268±0.06 g/cm3(Predicted)
Fp 161-166°C/2mm
storage temp. -20°C
solubility soluble in Methanol
pka18.23±0.30(Predicted)
form Crystalline Powder
color White to brown
Sensitive Air Sensitive
BRN 112190
CAS DataBase Reference5318-27-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36
WGK Germany 3
Hazard Note Harmful
HazardClass IRRITANT-HARMFUL, KEEP COLD
PackingGroup III
HS Code 29339900
MSDS Information
ProviderLanguage
6-Aminoindole English
SigmaAldrich English
ALFA English
6-Aminoindole Usage And Synthesis
Chemical PropertiesSolid
UsesReactant for preparation of:
  • Inhibitors of mammalian target of rapamycin (mTOR ) protein
  • Inhibitors of the AcrAB-TolC efflux pump
  • Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
  • Potent DNA-topoisomerase II poisons and anti-MDR agents
  • Protein kinase C θ (PKCθ) inhibitors
  • Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
  • Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain
  • 5,6-fused heteroaromatic ureas as TRPV1 antagonists
  • Allosteric enhancers of the A3 adenosine receptor
  • Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes
6-Aminoindole Preparation Products And Raw materials
Raw materialsNickel-->Potassium nitrate-->tert-Butyl methyl ether-->DBU-->Indoline-->Trichloroisocyanuric acid
Preparation ProductsIndole-6-boronic acid pinacol ester

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