6-Aminoindole

CAS No.：5318-27-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

6-Aminoindole Basic information

Product Name:	6-Aminoindole
Synonyms:	INDOLE-6-AMINE;1H-INDOL-6-AMINE;6-AMINOINDOLE;6-AMINO-1H-INDOLE;6-Indolamine;6-AMinoindole, 97+%;2,3-Dihydro-1H-indol-6-amine;6-Aminoindole ,98%
CAS:	5318-27-4
MF:	C8H8N2
MW:	132.16
EINECS:	627-713-5
Product Categories:	Simple Indoles;Building Blocks;Indoles and derivatives;Indole;Indoles;Heterocyclic Building Blocks;Heterocycle-Indole series
Mol File:	5318-27-4.mol

6-Aminoindole Chemical Properties

Melting point	75-79 °C
Boiling point	161-166°C 2mm
density	1.268±0.06 g/cm3(Predicted)
Fp	161-166°C/2mm
storage temp.	-20°C
solubility	soluble in Methanol
pka	18.23±0.30(Predicted)
form	Crystalline Powder
color	White to brown
Sensitive	Air Sensitive
BRN	112190
CAS DataBase Reference	5318-27-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-36/37/38
Safety Statements	26-36
WGK Germany	3
Hazard Note	Harmful
HazardClass	IRRITANT-HARMFUL, KEEP COLD
PackingGroup	III
HS Code	29339900

MSDS Information

Provider	Language
6-Aminoindole	English
SigmaAldrich	English
ALFA	English

6-Aminoindole Usage And Synthesis

Chemical Properties

Solid

Uses

Reactant for preparation of:

Inhibitors of mammalian target of rapamycin (mTOR ) protein
Inhibitors of the AcrAB-TolC efflux pump
Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
Potent DNA-topoisomerase II poisons and anti-MDR agents
Protein kinase C θ (PKCθ) inhibitors
Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain
5,6-fused heteroaromatic ureas as TRPV1 antagonists
Allosteric enhancers of the A3 adenosine receptor
Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes

6-Aminoindole Preparation Products And Raw materials

Raw materials	Nickel-->Potassium nitrate-->tert-Butyl methyl ether-->DBU-->Indoline-->Trichloroisocyanuric acid
Preparation Products	Indole-6-boronic acid pinacol ester

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873